Mayer RJ - Search Results

1

The oncoprotein gankyrin negatively regulates both p53 and RB by enhancing proteasomal degradation.

Higashitsuji H, Liu Y, Mayer RJ, Fujita J. Higashitsuji H, et al. Among authors: mayer rj. Cell Cycle. 2005 Oct;4(10):1335-7. doi: 10.4161/cc.4.10.2107. Epub 2005 Oct 17. Cell Cycle. 2005. PMID: 16177571

2

MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity.

Nagao T, Higashitsuji H, Nonoguchi K, Sakurai T, Dawson S, Mayer RJ, Itoh K, Fujita J. Nagao T, et al. Among authors: mayer rj. J Biol Chem. 2003 Mar 21;278(12):10668-74. doi: 10.1074/jbc.M206104200. Epub 2003 Jan 13. J Biol Chem. 2003. PMID: 12525503 Free article.

3

The crystal structure of gankyrin, an oncoprotein found in complexes with cyclin-dependent kinase 4, a 19 S proteasomal ATPase regulator, and the tumor suppressors Rb and p53.

Krzywda S, Brzozowski AM, Higashitsuji H, Fujita J, Welchman R, Dawson S, Mayer RJ, Wilkinson AJ. Krzywda S, et al. Among authors: mayer rj. J Biol Chem. 2004 Jan 9;279(2):1541-5. doi: 10.1074/jbc.M310265200. Epub 2003 Oct 22. J Biol Chem. 2004. PMID: 14573599 Free article.

4

The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53.

Higashitsuji H, Higashitsuji H, Itoh K, Sakurai T, Nagao T, Sumitomo Y, Masuda T, Dawson S, Shimada Y, Mayer RJ, Fujita J. Higashitsuji H, et al. Among authors: mayer rj. Cancer Cell. 2005 Jul;8(1):75-87. doi: 10.1016/j.ccr.2005.06.006. Cancer Cell. 2005. PMID: 16023600 Free article.

5

Gankyrin: a new oncoprotein and regulator of pRb and p53.

Dawson S, Higashitsuji H, Wilkinson AJ, Fujita J, Mayer RJ. Dawson S, et al. Among authors: mayer rj. Trends Cell Biol. 2006 May;16(5):229-33. doi: 10.1016/j.tcb.2006.03.001. Epub 2006 Apr 3. Trends Cell Biol. 2006. PMID: 16581249

6

Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas.

Higashitsuji H, Itoh K, Nagao T, Dawson S, Nonoguchi K, Kido T, Mayer RJ, Arii S, Fujita J. Higashitsuji H, et al. Among authors: mayer rj. Nat Med. 2000 Jan;6(1):96-9. doi: 10.1038/71600. Nat Med. 2000. PMID: 10613832

7

Gankyrin is an ankyrin-repeat oncoprotein that interacts with CDK4 kinase and the S6 ATPase of the 26 S proteasome.

Dawson S, Apcher S, Mee M, Higashitsuji H, Baker R, Uhle S, Dubiel W, Fujita J, Mayer RJ. Dawson S, et al. Among authors: mayer rj. J Biol Chem. 2002 Mar 29;277(13):10893-902. doi: 10.1074/jbc.M107313200. Epub 2002 Jan 4. J Biol Chem. 2002. PMID: 11779854 Free article.

8

Crystallization of gankyrin, an oncoprotein that interacts with CDK4 and the S6b (rpt3) ATPase of the 19S regulator of the 26S proteasome.

Krzywda S, Brzozowski AM, Al-Safty R, Welchman R, Mee M, Dawson S, Fujita J, Higashitsuji H, Mayer RJ, Wilkinson AJ. Krzywda S, et al. Among authors: mayer rj. Acta Crystallogr D Biol Crystallogr. 2003 Jul;59(Pt 7):1294-5. doi: 10.1107/s0907444903009892. Epub 2003 Jun 27. Acta Crystallogr D Biol Crystallogr. 2003. PMID: 12832791

9

Gankyrin, the 26 S proteasome, the cell cycle and cancer.

Mayer RJ, Fujita J. Mayer RJ, et al. Biochem Soc Trans. 2006 Nov;34(Pt 5):746-8. doi: 10.1042/BST0340746. Biochem Soc Trans. 2006. PMID: 17052188

10

Proteasomal interactors control activities as diverse as the cell cycle and glutaminergic neurotransmission.

Rezvani K, Mee M, Dawson S, McIlhinney J, Fujita J, Mayer RJ. Rezvani K, et al. Among authors: mayer rj. Biochem Soc Trans. 2003 Apr;31(2):470-3. doi: 10.1042/bst0310470. Biochem Soc Trans. 2003. PMID: 12653665

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