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Second-generation shRNA libraries covering the mouse and human genomes.
Silva JM, Li MZ, Chang K, Ge W, Golding MC, Rickles RJ, Siolas D, Hu G, Paddison PJ, Schlabach MR, Sheth N, Bradshaw J, Burchard J, Kulkarni A, Cavet G, Sachidanandam R, McCombie WR, Cleary MA, Elledge SJ, Hannon GJ. Silva JM, et al. Among authors: elledge sj. Nat Genet. 2005 Nov;37(11):1281-8. doi: 10.1038/ng1650. Epub 2005 Oct 2. Nat Genet. 2005. PMID: 16200065
Dicer is essential for mouse development.
Bernstein E, Kim SY, Carmell MA, Murchison EP, Alcorn H, Li MZ, Mills AA, Elledge SJ, Anderson KV, Hannon GJ. Bernstein E, et al. Among authors: elledge sj. Nat Genet. 2003 Nov;35(3):215-7. doi: 10.1038/ng1253. Epub 2003 Oct 5. Nat Genet. 2003. PMID: 14528307
A resource for large-scale RNA-interference-based screens in mammals.
Paddison PJ, Silva JM, Conklin DS, Schlabach M, Li M, Aruleba S, Balija V, O'Shaughnessy A, Gnoj L, Scobie K, Chang K, Westbrook T, Cleary M, Sachidanandam R, McCombie WR, Elledge SJ, Hannon GJ. Paddison PJ, et al. Among authors: elledge sj. Nature. 2004 Mar 25;428(6981):427-31. doi: 10.1038/nature02370. Nature. 2004. PMID: 15042091
A genetic screen for candidate tumor suppressors identifies REST.
Westbrook TF, Martin ES, Schlabach MR, Leng Y, Liang AC, Feng B, Zhao JJ, Roberts TM, Mandel G, Hannon GJ, Depinho RA, Chin L, Elledge SJ. Westbrook TF, et al. Among authors: elledge sj. Cell. 2005 Jun 17;121(6):837-48. doi: 10.1016/j.cell.2005.03.033. Cell. 2005. PMID: 15960972 Free article.
An open letter to cancer researchers.
Elledge SJ, Hannon GJ. Elledge SJ, et al. Science. 2005 Oct 21;310(5747):439-41. doi: 10.1126/science.310.5747.439b. Science. 2005. PMID: 16239460 No abstract available.
Lessons from Nature: microRNA-based shRNA libraries.
Chang K, Elledge SJ, Hannon GJ. Chang K, et al. Among authors: elledge sj. Nat Methods. 2006 Sep;3(9):707-14. doi: 10.1038/nmeth923. Nat Methods. 2006. PMID: 16929316 Review.
396 results