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Dehydroepiandrosterone (DHEA) metabolism in the brain: identification by liquid chromatography/mass spectrometry of the delta-4-isomer of DHEA and related steroids formed from androstenedione by mouse BV2 microglia.
Jellinck PH, Kaufmann M, Gottfried-Blackmore A, Croft G, Byford V, McEwen BS, Jones G, Bulloch K. Jellinck PH, et al. Among authors: bulloch k. J Steroid Biochem Mol Biol. 2006 Jan;98(1):41-7. doi: 10.1016/j.jsbmb.2005.07.006. Epub 2005 Oct 3. J Steroid Biochem Mol Biol. 2006. PMID: 16203131
Brain microglia express steroid-converting enzymes in the mouse.
Gottfried-Blackmore A, Sierra A, Jellinck PH, McEwen BS, Bulloch K. Gottfried-Blackmore A, et al. Among authors: bulloch k. J Steroid Biochem Mol Biol. 2008 Mar;109(1-2):96-107. doi: 10.1016/j.jsbmb.2007.12.013. Epub 2008 Feb 2. J Steroid Biochem Mol Biol. 2008. PMID: 18329265 Free PMC article.
7α-hydroxylation of dehydroepiandrosterone does not interfere with the activation of glucocorticoids by 11β-hydroxysteroid dehydrogenase in E(t)C cerebellar neurons.
Gottfried-Blackmore A, Jellinck PH, Vecchiarelli HA, Masheeb Z, Kaufmann M, McEwen BS, Bulloch K. Gottfried-Blackmore A, et al. Among authors: bulloch k. J Steroid Biochem Mol Biol. 2013 Nov;138:290-7. doi: 10.1016/j.jsbmb.2013.07.001. Epub 2013 Jul 12. J Steroid Biochem Mol Biol. 2013. PMID: 23851218
62 results