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Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibrosis cells.
Guerra L, Fanelli T, Favia M, Riccardi SM, Busco G, Cardone RA, Carrabino S, Weinman EJ, Reshkin SJ, Conese M, Casavola V. Guerra L, et al. Among authors: weinman ej. J Biol Chem. 2005 Dec 9;280(49):40925-33. doi: 10.1074/jbc.M505103200. Epub 2005 Oct 3. J Biol Chem. 2005. PMID: 16203733 Free article.
Cystic fibrosis transmembrane conductance regulator activation is reduced in the small intestine of Na+/H+ exchanger 3 regulatory factor 1 (NHERF-1)- but Not NHERF-2-deficient mice.
Broere N, Hillesheim J, Tuo B, Jorna H, Houtsmuller AB, Shenolikar S, Weinman EJ, Donowitz M, Seidler U, de Jonge HR, Hogema BM. Broere N, et al. Among authors: weinman ej. J Biol Chem. 2007 Dec 28;282(52):37575-84. doi: 10.1074/jbc.M704878200. Epub 2007 Oct 18. J Biol Chem. 2007. PMID: 17947234 Free article.
Tissue-specific regulation of sodium/proton exchanger isoform 3 activity in Na(+)/H(+) exchanger regulatory factor 1 (NHERF1) null mice. cAMP inhibition is differentially dependent on NHERF1 and exchange protein directly activated by cAMP in ileum versus proximal tubule.
Murtazina R, Kovbasnjuk O, Zachos NC, Li X, Chen Y, Hubbard A, Hogema BM, Steplock D, Seidler U, Hoque KM, Tse CM, De Jonge HR, Weinman EJ, Donowitz M. Murtazina R, et al. Among authors: weinman ej. J Biol Chem. 2007 Aug 24;282(34):25141-51. doi: 10.1074/jbc.M701910200. Epub 2007 Jun 19. J Biol Chem. 2007. PMID: 17580307 Free article.
226 results