Blain JF - Search Results

1

The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease.

Hirsch-Reinshagen V, Maia LF, Burgess BL, Blain JF, Naus KE, McIsaac SA, Parkinson PF, Chan JY, Tansley GH, Hayden MR, Poirier J, Van Nostrand W, Wellington CL. Hirsch-Reinshagen V, et al. Among authors: blain jf. J Biol Chem. 2005 Dec 30;280(52):43243-56. doi: 10.1074/jbc.M508781200. Epub 2005 Oct 5. J Biol Chem. 2005. PMID: 16207707 Free article.

2

Could lipoprotein lipase play a role in Alzheimer's disease?

Blain JF, Poirier J. Blain JF, et al. ScientificWorldJournal. 2004 Jul 20;4:531-5. doi: 10.1100/tsw.2004.111. ScientificWorldJournal. 2004. PMID: 15311328 Free PMC article. Review.

3

Cholesterol homeostasis and the pathophysiology of Alzheimer's disease.

Blain JF, Poirier J. Blain JF, et al. Expert Rev Neurother. 2004 Sep;4(5):823-9. doi: 10.1586/14737175.4.5.823. Expert Rev Neurother. 2004. PMID: 15853509 Review.

4

A deficit in astroglial organization causes the impaired reactive sprouting in human apolipoprotein E4 targeted replacement mice.

Blain JF, Sullivan PM, Poirier J. Blain JF, et al. Neurobiol Dis. 2006 Mar;21(3):505-14. doi: 10.1016/j.nbd.2005.08.010. Epub 2005 Sep 19. Neurobiol Dis. 2006. PMID: 16171999

5

A polymorphism in lipoprotein lipase affects the severity of Alzheimer's disease pathophysiology.

Blain JF, Aumont N, Théroux L, Dea D, Poirier J. Blain JF, et al. Eur J Neurosci. 2006 Sep;24(5):1245-51. doi: 10.1111/j.1460-9568.2006.05007.x. Epub 2006 Sep 8. Eur J Neurosci. 2006. PMID: 16965549

6

Pro-inflammatory cytokines modulate glial apolipoprotein E secretion.

Aleong R, Blain JF, Poirier J. Aleong R, et al. Among authors: blain jf. Curr Alzheimer Res. 2008 Feb;5(1):33-7. doi: 10.2174/156720508783884666. Curr Alzheimer Res. 2008. PMID: 18288929

7

A role for caveolin-1 in post-injury reactive neuronal plasticity.

Gaudreault SB, Blain JF, Gratton JP, Poirier J. Gaudreault SB, et al. Among authors: blain jf. J Neurochem. 2005 Feb;92(4):831-9. doi: 10.1111/j.1471-4159.2004.02917.x. J Neurochem. 2005. PMID: 15686485 Free article.

8

A role for lipoprotein lipase during synaptic remodeling in the adult mouse brain.

Blain JF, Paradis E, Gaudreault SB, Champagne D, Richard D, Poirier J. Blain JF, et al. Neurobiol Dis. 2004 Apr;15(3):510-9. doi: 10.1016/j.nbd.2003.12.001. Neurobiol Dis. 2004. PMID: 15056458

9

Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer's disease.

Blain JF, Bursavich MG, Freeman EA, Hrdlicka LA, Hodgdon HE, Chen T, Costa DE, Harrison BA, Kapadnis S, Murphy DA, Nolan S, Tu Z, Tang C, Burnett DA, Patzke H, Koenig G. Blain JF, et al. Alzheimers Res Ther. 2016 Aug 30;8(1):34. doi: 10.1186/s13195-016-0199-5. Alzheimers Res Ther. 2016. PMID: 27572246 Free PMC article.

10

Gamma Secretase Modulators: New Alzheimer's Drugs on the Horizon?

Bursavich MG, Harrison BA, Blain JF. Bursavich MG, et al. Among authors: blain jf. J Med Chem. 2016 Aug 25;59(16):7389-409. doi: 10.1021/acs.jmedchem.5b01960. Epub 2016 Apr 5. J Med Chem. 2016. PMID: 27007185 Review.

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