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Page 1
The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease.
Hirsch-Reinshagen V, Maia LF, Burgess BL, Blain JF, Naus KE, McIsaac SA, Parkinson PF, Chan JY, Tansley GH, Hayden MR, Poirier J, Van Nostrand W, Wellington CL. Hirsch-Reinshagen V, et al. Among authors: mcisaac sa. J Biol Chem. 2005 Dec 30;280(52):43243-56. doi: 10.1074/jbc.M508781200. Epub 2005 Oct 5. J Biol Chem. 2005. PMID: 16207707 Free article.
Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain.
Hirsch-Reinshagen V, Zhou S, Burgess BL, Bernier L, McIsaac SA, Chan JY, Tansley GH, Cohn JS, Hayden MR, Wellington CL. Hirsch-Reinshagen V, et al. Among authors: mcisaac sa. J Biol Chem. 2004 Sep 24;279(39):41197-207. doi: 10.1074/jbc.M407962200. Epub 2004 Jul 21. J Biol Chem. 2004. PMID: 15269218 Free article.
Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant A beta in plasma.
Burgess BL, McIsaac SA, Naus KE, Chan JY, Tansley GH, Yang J, Miao F, Ross CJ, van Eck M, Hayden MR, van Nostrand W, St George-Hyslop P, Westaway D, Wellington CL. Burgess BL, et al. Among authors: mcisaac sa. Neurobiol Dis. 2006 Oct;24(1):114-27. doi: 10.1016/j.nbd.2006.06.007. Epub 2006 Aug 8. Neurobiol Dis. 2006. PMID: 16899370
The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein.
Tansley GH, Burgess BL, Bryan MT, Su Y, Hirsch-Reinshagen V, Pearce J, Chan JY, Wilkinson A, Evans J, Naus KE, McIsaac S, Bromley K, Song W, Yang HC, Wang N, DeMattos RB, Wellington CL. Tansley GH, et al. J Lipid Res. 2007 May;48(5):1022-34. doi: 10.1194/jlr.M600542-JLR200. Epub 2007 Feb 10. J Lipid Res. 2007. PMID: 17293612 Free article.
Measuring cortisol and DHEA in fingernails: a pilot study.
Warnock F, McElwee K, Seo RJ, McIsaac S, Seim D, Ramirez-Aponte T, Macritchie KA, Young AH. Warnock F, et al. Neuropsychiatr Dis Treat. 2010 Feb 3;6:1-7. Neuropsychiatr Dis Treat. 2010. PMID: 20169040 Free PMC article.