Scrutton NS - Search Results

1

The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase.

Neeli R, Girvan HM, Lawrence A, Warren MJ, Leys D, Scrutton NS, Munro AW. Neeli R, et al. Among authors: scrutton ns. FEBS Lett. 2005 Oct 24;579(25):5582-8. doi: 10.1016/j.febslet.2005.09.023. Epub 2005 Sep 28. FEBS Lett. 2005. PMID: 16214136 Free article.

2

Effects of environment on flavin reactivity in morphinone reductase: analysis of enzymes displaying differential charge near the N-1 atom and C-2 carbonyl region of the active-site flavin.

Craig DH, Barna T, Moody PC, Bruce NC, Chapman SK, Munro AW, Scrutton NS. Craig DH, et al. Among authors: scrutton ns. Biochem J. 2001 Oct 15;359(Pt 2):315-23. doi: 10.1042/0264-6021:3590315. Biochem J. 2001. PMID: 11583577 Free PMC article.

3

Kinetic and structural basis of reactivity of pentaerythritol tetranitrate reductase with NADPH, 2-cyclohexenone, nitroesters, and nitroaromatic explosives.

Khan H, Harris RJ, Barna T, Craig DH, Bruce NC, Munro AW, Moody PC, Scrutton NS. Khan H, et al. Among authors: scrutton ns. J Biol Chem. 2002 Jun 14;277(24):21906-12. doi: 10.1074/jbc.M200637200. Epub 2002 Mar 28. J Biol Chem. 2002. PMID: 11923299 Free article.

4

Extensive conformational sampling in a ternary electron transfer complex.

Leys D, Basran J, Talfournier F, Sutcliffe MJ, Scrutton NS. Leys D, et al. Among authors: scrutton ns. Nat Struct Biol. 2003 Mar;10(3):219-25. doi: 10.1038/nsb894. Nat Struct Biol. 2003. PMID: 12567183

5

Kinetic, spectroscopic and thermodynamic characterization of the Mycobacterium tuberculosis adrenodoxin reductase homologue FprA.

McLean KJ, Scrutton NS, Munro AW. McLean KJ, et al. Among authors: scrutton ns. Biochem J. 2003 Jun 1;372(Pt 2):317-27. doi: 10.1042/BJ20021692. Biochem J. 2003. PMID: 12614197 Free PMC article.

6

Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1.

Finn RD, Basran J, Roitel O, Wolf CR, Munro AW, Paine MJ, Scrutton NS. Finn RD, et al. Among authors: scrutton ns. Eur J Biochem. 2003 Mar;270(6):1164-75. doi: 10.1046/j.1432-1033.2003.03474.x. Eur J Biochem. 2003. PMID: 12631275 Free article.

7

Molecular dissection of human methionine synthase reductase: determination of the flavin redox potentials in full-length enzyme and isolated flavin-binding domains.

Wolthers KR, Basran J, Munro AW, Scrutton NS. Wolthers KR, et al. Among authors: scrutton ns. Biochemistry. 2003 Apr 8;42(13):3911-20. doi: 10.1021/bi027290b. Biochemistry. 2003. PMID: 12667082

8

Electron transfer in human cytochrome P450 reductase.

Gutierrez A, Grunau A, Paine M, Munro AW, Wolf CR, Roberts GC, Scrutton NS. Gutierrez A, et al. Among authors: scrutton ns. Biochem Soc Trans. 2003 Jun;31(Pt 3):497-501. doi: 10.1042/bst0310497. Biochem Soc Trans. 2003. PMID: 12773143 Review.

9

Cytochromes P450: novel drug targets in the war against multidrug-resistant Mycobacterium tuberculosis.

Munro AW, McLean KJ, Marshall KR, Warman AJ, Lewis G, Roitel O, Sutcliffe MJ, Kemp CA, Modi S, Scrutton NS, Leys D. Munro AW, et al. Among authors: scrutton ns. Biochem Soc Trans. 2003 Jun;31(Pt 3):625-30. doi: 10.1042/bst0310625. Biochem Soc Trans. 2003. PMID: 12773169 Review.

10

Interflavin electron transfer in human cytochrome P450 reductase is enhanced by coenzyme binding. Relaxation kinetic studies with coenzyme analogues.

Gutierrez A, Munro AW, Grunau A, Wolf CR, Scrutton NS, Roberts GC. Gutierrez A, et al. Among authors: scrutton ns. Eur J Biochem. 2003 Jun;270(12):2612-21. doi: 10.1046/j.1432-1033.2003.03633.x. Eur J Biochem. 2003. PMID: 12787027 Free article.

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