Tan J - Search Results

1

Perhydroquinolylbenzamides as novel inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.

Coppola GM, Kukkola PJ, Stanton JL, Neubert AD, Marcopulos N, Bilci NA, Wang H, Tomaselli HC, Tan J, Aicher TD, Knorr DC, Jeng AY, Dardik B, Chatelain RE. Coppola GM, et al. Among authors: tan j. J Med Chem. 2005 Oct 20;48(21):6696-712. doi: 10.1021/jm058228q. J Med Chem. 2005. PMID: 16220986

2

Anilides of (R)-trifluoro-2-hydroxy-2-methylpropionic acid as inhibitors of pyruvate dehydrogenase kinase.

Bebernitz GR, Aicher TD, Stanton JL, Gao J, Shetty SS, Knorr DC, Strohschein RJ, Tan J, Brand LJ, Liu C, Wang WH, Vinluan CC, Kaplan EL, Dragland CJ, DelGrande D, Islam A, Lozito RJ, Liu X, Maniara WM, Mann WR. Bebernitz GR, et al. Among authors: tan j. J Med Chem. 2000 Jun 1;43(11):2248-57. doi: 10.1021/jm0000923. J Med Chem. 2000. PMID: 10841803

3

Synthesis and biological activity of potent heterocyclic thiol-based inhibitors of endothelin-converting enzyme-1.

Firooznia F, Gude C, Chan K, Tan J, Fink CA, Savage P, Beil ME, Bruseo CW, Trapani AJ, Jeng AY. Firooznia F, et al. Among authors: tan j. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3059-62. doi: 10.1016/s0960-894x(02)00683-2. Bioorg Med Chem Lett. 2002. PMID: 12372501

4

Inhibition of peptidylglycine alpha-amidating monooxygenase by N-substituted homocysteine analogs.

Erion MD, Tan J, Wong M, Jeng AY. Erion MD, et al. Among authors: tan j. J Med Chem. 1994 Dec 23;37(26):4430-7. doi: 10.1021/jm00052a002. J Med Chem. 1994. PMID: 7528281

5

Potent and selective non-peptidic inhibitors of endothelin-converting enzyme-1 with sustained duration of action.

De Lombaert S, Blanchard L, Stamford LB, Tan J, Wallace EM, Satoh Y, Fitt J, Hoyer D, Simonsbergen D, Moliterni J, Marcopoulos N, Savage P, Chou M, Trapani AJ, Jeng AY. De Lombaert S, et al. Among authors: tan j. J Med Chem. 2000 Feb 10;43(3):488-504. doi: 10.1021/jm990507o. J Med Chem. 2000. PMID: 10669576

6

Synthesis and biological activity of phenoxyphenyl oxamic acid derivatives related to L-thyronine.

Stanton JL, Cahill E, Dotson R, Tan J, Tomaselli HC, Wasvary JM, Stephan ZF, Steele RE. Stanton JL, et al. Among authors: tan j. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1661-3. doi: 10.1016/s0960-894x(00)00309-7. Bioorg Med Chem Lett. 2000. PMID: 10937719

7

Suppression of substance P biosynthesis in sensory neurons of dorsal root ganglion by prodrug esters of potent peptidylglycine alpha-amidating monooxygenase inhibitors.

Jeng AY, Fujimoto RA, Chou M, Tan J, Erion MD. Jeng AY, et al. Among authors: tan j. J Biol Chem. 1997 Jun 6;272(23):14666-71. doi: 10.1074/jbc.272.23.14666. J Biol Chem. 1997. PMID: 9169429 Free article.

8

4-Substituted-7-N-alkyl-N-acetyl 2-aminobenzothiazole amides: drug-like and non-xanthine based A2B adenosine receptor antagonists.

Cheung AW, Brinkman J, Firooznia F, Flohr A, Grimsby J, Gubler ML, Guertin K, Hamid R, Marcopulos N, Norcross RD, Qi L, Ramsey G, Tan J, Wen Y, Sarabu R. Cheung AW, et al. Among authors: tan j. Bioorg Med Chem Lett. 2010 Jul 15;20(14):4140-6. doi: 10.1016/j.bmcl.2010.05.056. Epub 2010 May 20. Bioorg Med Chem Lett. 2010. PMID: 20541935

9

Discovery of benzothiazole-based adenosine A2B receptor antagonists with improved A2A selectivity.

Firooznia F, Cheung AW, Brinkman J, Grimsby J, Gubler ML, Hamid R, Marcopulos N, Ramsey G, Tan J, Wen Y, Sarabu R. Firooznia F, et al. Among authors: tan j. Bioorg Med Chem Lett. 2011 Apr 1;21(7):1933-6. doi: 10.1016/j.bmcl.2011.02.053. Epub 2011 Feb 17. Bioorg Med Chem Lett. 2011. PMID: 21388809

10

Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetes.

Qian Y, Wertheimer SJ, Ahmad M, Cheung AW, Firooznia F, Hamilton MM, Hayden S, Li S, Marcopulos N, McDermott L, Tan J, Yun W, Guo L, Pamidimukkala A, Chen Y, Huang KS, Ramsey GB, Whittard T, Conde-Knape K, Taub R, Rondinone CM, Tilley J, Bolin D. Qian Y, et al. Among authors: tan j. J Med Chem. 2011 Apr 14;54(7):2433-46. doi: 10.1021/jm101580m. Epub 2011 Mar 17. J Med Chem. 2011. PMID: 21413799

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