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Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism.
Werts C, Tapping RI, Mathison JC, Chuang TH, Kravchenko V, Saint Girons I, Haake DA, Godowski PJ, Hayashi F, Ozinsky A, Underhill DM, Kirschning CJ, Wagner H, Aderem A, Tobias PS, Ulevitch RJ. Werts C, et al. Nat Immunol. 2001 Apr;2(4):346-52. doi: 10.1038/86354. Nat Immunol. 2001. PMID: 11276206
First evidence for a restriction-modification system in Leptospira sp.
Brenot A, Werts C, Ottone C, Sertour N, Charon NW, Postic D, Baranton G, Saint Girons I. Brenot A, et al. Among authors: werts c. FEMS Microbiol Lett. 2001 Jul 24;201(2):139-43. doi: 10.1111/j.1574-6968.2001.tb10747.x. FEMS Microbiol Lett. 2001. PMID: 11470352
A methylated phosphate group and four amide-linked acyl chains in leptospira interrogans lipid A. The membrane anchor of an unusual lipopolysaccharide that activates TLR2.
Que-Gewirth NL, Ribeiro AA, Kalb SR, Cotter RJ, Bulach DM, Adler B, Girons IS, Werts C, Raetz CR. Que-Gewirth NL, et al. Among authors: werts c. J Biol Chem. 2004 Jun 11;279(24):25420-9. doi: 10.1074/jbc.M400598200. Epub 2004 Mar 24. J Biol Chem. 2004. PMID: 15044492 Free PMC article.
Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway.
Werts C, le Bourhis L, Liu J, Magalhaes JG, Carneiro LA, Fritz JH, Stockinger S, Balloy V, Chignard M, Decker T, Philpott DJ, Ma X, Girardin SE. Werts C, et al. Eur J Immunol. 2007 Sep;37(9):2499-508. doi: 10.1002/eji.200737069. Eur J Immunol. 2007. PMID: 17705131 Free article.
88 results