Altmann KH - Search Results

1

Scaffolds for microtubule inhibition through extensive modification of the epothilone template.

Cachoux F, Isarno T, Wartmann M, Altmann KH. Cachoux F, et al. Among authors: altmann kh. Angew Chem Int Ed Engl. 2005 Dec 1;44(45):7469-73. doi: 10.1002/anie.200501760. Angew Chem Int Ed Engl. 2005. PMID: 16240301 No abstract available.

2

The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents.

Carlomagno T, Blommers MJ, Meiler J, Jahnke W, Schupp T, Petersen F, Schinzer D, Altmann KH, Griesinger C. Carlomagno T, et al. Among authors: altmann kh. Angew Chem Int Ed Engl. 2003 Jun 6;42(22):2511-5. doi: 10.1002/anie.200351276. Angew Chem Int Ed Engl. 2003. PMID: 12800173 No abstract available.

3

Design, synthesis, and biological properties of highly potent epothilone B analogues.

Nicolaou KC, Sasmal PK, Rassias G, Reddy MV, Altmann KH, Wartmann M, O'Brate A, Giannakakou P. Nicolaou KC, et al. Among authors: altmann kh. Angew Chem Int Ed Engl. 2003 Aug 4;42(30):3515-20. doi: 10.1002/anie.200351819. Angew Chem Int Ed Engl. 2003. PMID: 12900969 No abstract available.

4

4. The natural products epothilones A and B as lead structures for anticancer drug discovery: chemistry, biology, and SAR studies.

Altmann KH, Flörsheimer A, O'Reilly T, Wartmann M. Altmann KH, et al. Prog Med Chem. 2004;42:171-205. doi: 10.1016/S0079-6468(04)42004-9. Prog Med Chem. 2004. PMID: 15003721 Review. No abstract available.

5

Patupilone (epothilone B, EPO906) inhibits growth and metastasis of experimental prostate tumors in vivo.

O'Reilly T, McSheehy PM, Wenger F, Hattenberger M, Muller M, Vaxelaire J, Altmann KH, Wartmann M. O'Reilly T, et al. Among authors: altmann kh. Prostate. 2005 Nov 1;65(3):231-40. doi: 10.1002/pros.20289. Prostate. 2005. PMID: 15948135

6

Total synthesis and biological assessment of benzimidazole-based analogues of epothilone A: ambivalent effects on cancer cell growth inhibition.

Cachoux F, Isarno T, Wartmann M, Altmann KH. Cachoux F, et al. Among authors: altmann kh. Chembiochem. 2006 Jan;7(1):54-7. doi: 10.1002/cbic.200500351. Chembiochem. 2006. PMID: 16345113 No abstract available.

7

Design and synthesis of 12-aza-epothilones (azathilones)--"non-natural" natural products with potent anticancer activity.

Feyen F, Gertsch J, Wartmann M, Altmann KH. Feyen F, et al. Among authors: altmann kh. Angew Chem Int Ed Engl. 2006 Sep 4;45(35):5880-5. doi: 10.1002/anie.200601359. Angew Chem Int Ed Engl. 2006. PMID: 16871640 No abstract available.

8

Structure-activity relationships in side-chain-modified epothilone analogues--how important is the position of the nitrogen atom?

Bold G, Wojeik S, Caravatti G, Lindauer R, Stierlin C, Gertsch J, Wartmann M, Altmann KH. Bold G, et al. Among authors: altmann kh. ChemMedChem. 2006 Jan;1(1):37-40. doi: 10.1002/cmdc.200500051. ChemMedChem. 2006. PMID: 16892331 No abstract available.

9

Total synthesis and biological evaluation of a C(10)/C(12)-phenylene-bridged analog of epothilone D.

End N, Furet P, van Campenhout N, Wartmann M, Altmann KH. End N, et al. Among authors: altmann kh. Chem Biodivers. 2004 Nov;1(11):1771-84. doi: 10.1002/cbdv.200490133. Chem Biodivers. 2004. PMID: 17191815

10

Epothilones as lead structures for the synthesis-based discovery of new chemotypes for microtubule stabilization.

Feyen F, Cachoux F, Gertsch J, Wartmann M, Altmann KH. Feyen F, et al. Among authors: altmann kh. Acc Chem Res. 2008 Jan;41(1):21-31. doi: 10.1021/ar700157x. Epub 2007 Dec 27. Acc Chem Res. 2008. PMID: 18159935 Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

176 results

Search Page

Filters