Mazza F - Search Results

1

N-Hydroxyurea as zinc binding group in matrix metalloproteinase inhibition: mode of binding in a complex with MMP-8.

Campestre C, Agamennone M, Tortorella P, Preziuso S, Biasone A, Gavuzzo E, Pochetti G, Mazza F, Hiller O, Tschesche H, Consalvi V, Gallina C. Campestre C, et al. Among authors: mazza f. Bioorg Med Chem Lett. 2006 Jan 1;16(1):20-4. doi: 10.1016/j.bmcl.2005.09.057. Epub 2005 Oct 18. Bioorg Med Chem Lett. 2006. PMID: 16242329

2

Synthesis and evaluation of new tripeptide phosphonate inhibitors of MMP-8 and MMP-2.

Agamennone M, Campestre C, Preziuso S, Consalvi V, Crucianelli M, Mazza F, Politi V, Ragno R, Tortorella P, Gallina C. Agamennone M, et al. Among authors: mazza f. Eur J Med Chem. 2005 Mar;40(3):271-9. doi: 10.1016/j.ejmech.2004.10.013. Epub 2005 Jan 19. Eur J Med Chem. 2005. PMID: 15725496

3

Design, modelling, synthesis and biological evaluation of peptidomimetic phosphinates as inhibitors of matrix metalloproteinases MMP-2 and MMP-8.

Bianchini G, Aschi M, Cavicchio G, Crucianelli M, Preziuso S, Gallina C, Nastari A, Gavuzzo E, Mazza F. Bianchini G, et al. Among authors: mazza f. Bioorg Med Chem. 2005 Aug 1;13(15):4740-9. doi: 10.1016/j.bmc.2005.04.079. Bioorg Med Chem. 2005. PMID: 15935680

4

Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates.

Pochetti G, Gavuzzo E, Campestre C, Agamennone M, Tortorella P, Consalvi V, Gallina C, Hiller O, Tschesche H, Tucker PA, Mazza F. Pochetti G, et al. Among authors: mazza f. J Med Chem. 2006 Feb 9;49(3):923-31. doi: 10.1021/jm050787+. J Med Chem. 2006. PMID: 16451058

5

alpha-Biphenylsulfonylamino 2-methylpropyl phosphonates: enantioselective synthesis and selective inhibition of MMPs.

Biasone A, Tortorella P, Campestre C, Agamennone M, Preziuso S, Chiappini M, Nuti E, Carelli P, Rossello A, Mazza F, Gallina C. Biasone A, et al. Among authors: mazza f. Bioorg Med Chem. 2007 Jan 15;15(2):791-9. doi: 10.1016/j.bmc.2006.10.047. Epub 2006 Oct 25. Bioorg Med Chem. 2007. PMID: 17088065

6

Stereoselectivity by enantiomeric inhibitors of matrix metalloproteinase-8: new insights from molecular dynamics simulations.

Aschi M, Besker N, Re N, Pochetti G, Coletti C, Gallina C, Mazza F. Aschi M, et al. Among authors: mazza f. J Med Chem. 2007 Jan 25;50(2):211-8. doi: 10.1021/jm0608457. J Med Chem. 2007. PMID: 17228863

7

Extra binding region induced by non-zinc chelating inhibitors into the S1' subsite of matrix metalloproteinase 8 (MMP-8).

Pochetti G, Montanari R, Gege C, Chevrier C, Taveras AG, Mazza F. Pochetti G, et al. Among authors: mazza f. J Med Chem. 2009 Feb 26;52(4):1040-9. doi: 10.1021/jm801166j. J Med Chem. 2009. PMID: 19173605

8

Two crystal structures of human neutrophil collagenase, one complexed with a primed- and the other with an unprimed-side inhibitor: implications for drug design.

Gavuzzo E, Pochetti G, Mazza F, Gallina C, Gorini B, D'Alessio S, Pieper M, Tschesche H, Tucker PA. Gavuzzo E, et al. Among authors: mazza f. J Med Chem. 2000 Sep 7;43(18):3377-85. doi: 10.1021/jm9909589. J Med Chem. 2000. PMID: 10978185

9

Exploring the interest of 1,2-dithiolane ring system in peptide chemistry. Synthesis of a chemotactic tripeptide and x-ray crystal structure of a 4-amino-1,2-dithiolane-4-carboxylic acid derivative.

Morera E, Lucente G, Ortar G, Nalli M, Mazza F, Gavuzzo E, Spisani S. Morera E, et al. Among authors: mazza f. Bioorg Med Chem. 2002 Jan;10(1):147-57. doi: 10.1016/s0968-0896(01)00256-5. Bioorg Med Chem. 2002. PMID: 11738616

10

Computational study of the catalytic domain of human neutrophil collagenase. specific role of the S3 and S'3 subsites in the interaction with a phosphonate inhibitor.

Aschi M, Roccatano D, Di Nola A, Gallina C, Gavuzzo E, Pochetti G, Pieper M, Tschesche H, Mazza F. Aschi M, et al. Among authors: mazza f. J Comput Aided Mol Des. 2002 Mar;16(3):213-25. doi: 10.1023/a:1020178822319. J Comput Aided Mol Des. 2002. PMID: 12363219

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