Leslie NR - Search Results

1

Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice.

Bayascas JR, Leslie NR, Parsons R, Fleming S, Alessi DR. Bayascas JR, et al. Among authors: leslie nr. Curr Biol. 2005 Oct 25;15(20):1839-46. doi: 10.1016/j.cub.2005.08.066. Curr Biol. 2005. PMID: 16243031 Free article.

2

Analysis of the cellular functions of PTEN using catalytic domain and C-terminal mutations: differential effects of C-terminal deletion on signalling pathways downstream of phosphoinositide 3-kinase.

Leslie NR, Gray A, Pass I, Orchiston EA, Downes CP. Leslie NR, et al. Biochem J. 2000 Mar 15;346 Pt 3(Pt 3):827-33. Biochem J. 2000. PMID: 10698713 Free PMC article.

3

A role for the actin cytoskeleton in the hormonal and growth-factor-mediated activation of protein kinase B.

Peyrollier K, Hajduch E, Gray A, Litherland GJ, Prescott AR, Leslie NR, Hundal HS. Peyrollier K, et al. Among authors: leslie nr. Biochem J. 2000 Dec 15;352 Pt 3(Pt 3):617-22. Biochem J. 2000. PMID: 11104665 Free PMC article.

4

Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions.

Leslie NR, Bennett D, Gray A, Pass I, Hoang-Xuan K, Downes CP. Leslie NR, et al. Biochem J. 2001 Jul 15;357(Pt 2):427-35. doi: 10.1042/0264-6021:3570427. Biochem J. 2001. PMID: 11439092 Free PMC article.

5

Antagonism of PI 3-kinase-dependent signalling pathways by the tumour suppressor protein, PTEN.

Downes CP, Bennett D, McConnachie G, Leslie NR, Pass I, MacPhee C, Patel L, Gray A. Downes CP, et al. Among authors: leslie nr. Biochem Soc Trans. 2001 Nov;29(Pt 6):846-51. doi: 10.1042/0300-5127:0290846. Biochem Soc Trans. 2001. PMID: 11709086 Review.

6

Phosphoinositide-regulated kinases and phosphoinositide phosphatases.

Leslie NR, Biondi RM, Alessi DR. Leslie NR, et al. Chem Rev. 2001 Aug;101(8):2365-80. doi: 10.1021/cr000091i. Chem Rev. 2001. PMID: 11749378 Review. No abstract available.

7

PTEN: The down side of PI 3-kinase signalling.

Leslie NR, Downes CP. Leslie NR, et al. Cell Signal. 2002 Apr;14(4):285-95. doi: 10.1016/s0898-6568(01)00234-0. Cell Signal. 2002. PMID: 11858936 Review.

8

Redox regulation of PI 3-kinase signalling via inactivation of PTEN.

Leslie NR, Bennett D, Lindsay YE, Stewart H, Gray A, Downes CP. Leslie NR, et al. EMBO J. 2003 Oct 15;22(20):5501-10. doi: 10.1093/emboj/cdg513. EMBO J. 2003. PMID: 14532122 Free PMC article.

9

The tumour-suppressor function of PTEN requires an N-terminal lipid-binding motif.

Walker SM, Leslie NR, Perera NM, Batty IH, Downes CP. Walker SM, et al. Among authors: leslie nr. Biochem J. 2004 Apr 15;379(Pt 2):301-7. doi: 10.1042/BJ20031839. Biochem J. 2004. PMID: 14711368 Free PMC article.

10

PTEN function: how normal cells control it and tumour cells lose it.

Leslie NR, Downes CP. Leslie NR, et al. Biochem J. 2004 Aug 15;382(Pt 1):1-11. doi: 10.1042/BJ20040825. Biochem J. 2004. PMID: 15193142 Free PMC article. Review.

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