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Resistin-like molecule beta activates MAPKs, suppresses insulin signaling in hepatocytes, and induces diabetes, hyperlipidemia, and fatty liver in transgenic mice on a high fat diet.
Kushiyama A, Shojima N, Ogihara T, Inukai K, Sakoda H, Fujishiro M, Fukushima Y, Anai M, Ono H, Horike N, Viana AY, Uchijima Y, Nishiyama K, Shimosawa T, Fujita T, Katagiri H, Oka Y, Kurihara H, Asano T. Kushiyama A, et al. Among authors: asano t. J Biol Chem. 2005 Dec 23;280(51):42016-25. doi: 10.1074/jbc.M503065200. Epub 2005 Oct 21. J Biol Chem. 2005. PMID: 16243841 Free article.
Resistin is regulated by C/EBPs, PPARs, and signal-transducing molecules.
Song H, Shojima N, Sakoda H, Ogihara T, Fujishiro M, Katagiri H, Anai M, Onishi Y, Ono H, Inukai K, Fukushima Y, Kikuchi M, Shimano H, Yamada N, Oka Y, Asano T. Song H, et al. Among authors: asano t. Biochem Biophys Res Commun. 2002 Nov 29;299(2):291-8. doi: 10.1016/s0006-291x(02)02551-2. Biochem Biophys Res Commun. 2002. PMID: 12437985
Differing roles of Akt and serum- and glucocorticoid-regulated kinase in glucose metabolism, DNA synthesis, and oncogenic activity.
Sakoda H, Gotoh Y, Katagiri H, Kurokawa M, Ono H, Onishi Y, Anai M, Ogihara T, Fujishiro M, Fukushima Y, Abe M, Shojima N, Kikuchi M, Oka Y, Hirai H, Asano T. Sakoda H, et al. Among authors: asano t. J Biol Chem. 2003 Jul 11;278(28):25802-7. doi: 10.1074/jbc.M301127200. Epub 2003 May 6. J Biol Chem. 2003. PMID: 12734207 Free article.
A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis.
Anai M, Shojima N, Katagiri H, Ogihara T, Sakoda H, Onishi Y, Ono H, Fujishiro M, Fukushima Y, Horike N, Viana A, Kikuchi M, Noguchi N, Takahashi S, Takata K, Oka Y, Uchijima Y, Kurihara H, Asano T. Anai M, et al. Among authors: asano t. J Biol Chem. 2005 May 6;280(18):18525-35. doi: 10.1074/jbc.M500586200. Epub 2005 Mar 7. J Biol Chem. 2005. PMID: 15753085 Free article.
Glycogen debranching enzyme association with beta-subunit regulates AMP-activated protein kinase activity.
Sakoda H, Fujishiro M, Fujio J, Shojima N, Ogihara T, Kushiyama A, Fukushima Y, Anai M, Ono H, Kikuchi M, Horike N, Viana AY, Uchijima Y, Kurihara H, Asano T. Sakoda H, et al. Among authors: asano t. Am J Physiol Endocrinol Metab. 2005 Sep;289(3):E474-81. doi: 10.1152/ajpendo.00003.2005. Epub 2005 May 10. Am J Physiol Endocrinol Metab. 2005. PMID: 15886229 Free article.
Regulation of gut-derived resistin-like molecule beta expression by nutrients.
Fujio J, Kushiyama A, Sakoda H, Fujishiro M, Ogihara T, Fukushima Y, Anai M, Horike N, Kamata H, Uchijima Y, Kurihara H, Asano T. Fujio J, et al. Among authors: asano t. Diabetes Res Clin Pract. 2008 Jan;79(1):2-10. doi: 10.1016/j.diabres.2007.04.015. Epub 2007 Oct 23. Diabetes Res Clin Pract. 2008. PMID: 17936398
AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver.
Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T. Horike N, et al. Among authors: asano t. J Biol Chem. 2008 Dec 5;283(49):33902-10. doi: 10.1074/jbc.M802537200. Epub 2008 Sep 17. J Biol Chem. 2008. PMID: 18801732 Free PMC article.
2,983 results