Gajewiak J - Search Results

1

New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors.

Prestwich GD, Xu Y, Qian L, Gajewiak J, Jiang G. Prestwich GD, et al. Among authors: gajewiak j. Biochem Soc Trans. 2005 Dec;33(Pt 6):1357-61. doi: 10.1042/BST0331357. Biochem Soc Trans. 2005. PMID: 16246118 Review.

2

Aminooxy pluronics: synthesis and preparation of glycosaminoglycan adducts.

Gajewiak J, Cai S, Shu XZ, Prestwich GD. Gajewiak J, et al. Biomacromolecules. 2006 Jun;7(6):1781-9. doi: 10.1021/bm060111b. Biomacromolecules. 2006. PMID: 16768398

3

Synthesis and molecular recognition of phosphatidylinositol-3-methylenephosphate.

Gajewiak J, Xu Y, Lee SA, Kutateladze TG, Prestwich GD. Gajewiak J, et al. Org Lett. 2006 Jun 22;8(13):2811-3. doi: 10.1021/ol060903i. Org Lett. 2006. PMID: 16774263 Free PMC article.

4

Alpha-substituted phosphonate analogues of lysophosphatidic acid (LPA) selectively inhibit production and action of LPA.

Jiang G, Xu Y, Fujiwara Y, Tsukahara T, Tsukahara R, Gajewiak J, Tigyi G, Prestwich GD. Jiang G, et al. Among authors: gajewiak j. ChemMedChem. 2007 May;2(5):679-90. doi: 10.1002/cmdc.200600280. ChemMedChem. 2007. PMID: 17443831 Free PMC article.

5

Alkoxymethylenephosphonate analogues of (Lyso) phosphatidic acid stimulate signaling networks coupled to the LPA2 receptor.

Gajewiak J, Tsukahara R, Tsukahara T, Fujiwara Y, Yu S, Lu Y, Murph M, Mills GB, Tigyi G, Prestwich GD. Gajewiak J, et al. ChemMedChem. 2007 Dec;2(12):1789-98. doi: 10.1002/cmdc.200700111. ChemMedChem. 2007. PMID: 17952880

6

Synthesis, pharmacology, and cell biology of sn-2-aminooxy analogues of lysophosphatidic acid.

Gajewiak J, Tsukahara R, Fujiwara Y, Tigyi G, Prestwich GD. Gajewiak J, et al. Org Lett. 2008 Mar 20;10(6):1111-4. doi: 10.1021/ol7030747. Epub 2008 Feb 20. Org Lett. 2008. PMID: 18284246 Free PMC article.

7

Phosphatase-resistant analogues of lysophosphatidic acid: agonists promote healing, antagonists and autotaxin inhibitors treat cancer.

Prestwich GD, Gajewiak J, Zhang H, Xu X, Yang G, Serban M. Prestwich GD, et al. Among authors: gajewiak j. Biochim Biophys Acta. 2008 Sep;1781(9):588-94. doi: 10.1016/j.bbalip.2008.03.008. Epub 2008 Apr 8. Biochim Biophys Acta. 2008. PMID: 18454946 Free PMC article. Review.

8

Dual activity lysophosphatidic acid receptor pan-antagonist/autotaxin inhibitor reduces breast cancer cell migration in vitro and causes tumor regression in vivo.

Zhang H, Xu X, Gajewiak J, Tsukahara R, Fujiwara Y, Liu J, Fells JI, Perygin D, Parrill AL, Tigyi G, Prestwich GD. Zhang H, et al. Among authors: gajewiak j. Cancer Res. 2009 Jul 1;69(13):5441-9. doi: 10.1158/0008-5472.CAN-09-0302. Epub 2009 Jun 9. Cancer Res. 2009. PMID: 19509223 Free PMC article.

9

Metabolically stabilized derivatives of phosphatidylinositol 4-phosphate: synthesis and applications.

He J, Gajewiak J, Scott JL, Gong D, Ali M, Best MD, Prestwich GD, Stahelin RV, Kutateladze TG. He J, et al. Among authors: gajewiak j. Chem Biol. 2011 Oct 28;18(10):1312-9. doi: 10.1016/j.chembiol.2011.07.022. Chem Biol. 2011. PMID: 22035800 Free PMC article.

10

Critical residue properties for potency and selectivity of α-Conotoxin RgIA towards α9α10 nicotinic acetylcholine receptors.

Huynh PN, Harvey PJ, Gajewiak J, Craik DJ, Michael McIntosh J. Huynh PN, et al. Among authors: gajewiak j. Biochem Pharmacol. 2020 Nov;181:114124. doi: 10.1016/j.bcp.2020.114124. Epub 2020 Jun 25. Biochem Pharmacol. 2020. PMID: 32593612 Free PMC article.

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