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Human XPG nuclease structure, assembly, and activities with insights for neurodegeneration and cancer from pathogenic mutations.
Tsutakawa SE, Sarker AH, Ng C, Arvai AS, Shin DS, Shih B, Jiang S, Thwin AC, Tsai MS, Willcox A, Her MZ, Trego KS, Raetz AG, Rosenberg D, Bacolla A, Hammel M, Griffith JD, Cooper PK, Tainer JA. Tsutakawa SE, et al. Among authors: shin ds. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):14127-14138. doi: 10.1073/pnas.1921311117. Epub 2020 Jun 10. Proc Natl Acad Sci U S A. 2020. PMID: 32522879 Free PMC article.
Amyotrophic lateral sclerosis.
Perry JJ, Shin DS, Tainer JA. Perry JJ, et al. Among authors: shin ds. Adv Exp Med Biol. 2010;685:9-20. doi: 10.1007/978-1-4419-6448-9_2. Adv Exp Med Biol. 2010. PMID: 20687491 Review.
Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes.
Tsutakawa SE, Shin DS, Mol CD, Izumi T, Arvai AS, Mantha AK, Szczesny B, Ivanov IN, Hosfield DJ, Maiti B, Pique ME, Frankel KA, Hitomi K, Cunningham RP, Mitra S, Tainer JA. Tsutakawa SE, et al. Among authors: shin ds. J Biol Chem. 2013 Mar 22;288(12):8445-8455. doi: 10.1074/jbc.M112.422774. Epub 2013 Jan 25. J Biol Chem. 2013. PMID: 23355472 Free PMC article.
554 results