Kudoh T - Search Results

1

Synthesis and biological activity of cyclic ADP-carbocyclic-ribose analogs: structure-activity relationship and conformational analysis of N-1-carbocyclic-ribose moiety.

Kudoh T, Fukuoka M, Shuto S, Matsuda A. Kudoh T, et al. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):655-8. doi: 10.1081/ncn-200060167. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16248007

2

Convergent synthesis and unexpected Ca(2+)-mobilizing activity of 8-substituted analogues of cyclic ADP-carbocyclic-ribose, a stable mimic of the Ca(2+)-mobilizing second messenger cyclic ADP-ribose.

Shuto S, Fukuoka M, Kudoh T, Garnham C, Galione A, Potter BV, Matsuda A. Shuto S, et al. Among authors: kudoh t. J Med Chem. 2003 Oct 23;46(22):4741-9. doi: 10.1021/jm030227f. J Med Chem. 2003. PMID: 14561093

3

Synthesis of stable and cell-type selective analogues of cyclic ADP-ribose, a Ca(2+)-mobilizing second messenger. Structure--activity relationship of the N1-ribose moiety.

Kudoh T, Fukuoka M, Ichikawa S, Murayama T, Ogawa Y, Hashii M, Higashida H, Kunerth S, Weber K, Guse AH, Potter BV, Matsuda A, Shuto S. Kudoh T, et al. J Am Chem Soc. 2005 Jun 22;127(24):8846-55. doi: 10.1021/ja050732x. J Am Chem Soc. 2005. PMID: 15954793

4

Amplification of depolarization-induced and ryanodine-sensitive cytosolic Ca2+ elevation by synthetic carbocyclic analogs of cyclic ADP-ribose and their antagonistic effects in NG108-15 neuronal cells.

Hashii M, Shuto S, Fukuoka M, Kudoh T, Matsuda A, Higashida H. Hashii M, et al. Among authors: kudoh t. J Neurochem. 2005 Jul;94(2):316-23. doi: 10.1111/j.1471-4159.2005.03197.x. J Neurochem. 2005. PMID: 15998283 Free article.

5

Synthesis of cyclic ADP-carbocylcic-xylose and its 3"-O-methyl analogue as stable and potent Ca2+ -mobilizing agents.

Kudoh T, Matsuda A, Shuto S, Murayama T, Ogawa Y. Kudoh T, et al. Nucleosides Nucleotides Nucleic Acids. 2006;25(4-6):583-99. doi: 10.1080/15257770600685867. Nucleosides Nucleotides Nucleic Acids. 2006. PMID: 16838847 Free article.

6

Synthesis and biological activity of 4'',6''-unsaturated cyclic ADP-carbocyclic-ribose.

Kudoh T, Murayama T, Matsuda A, Shuto S. Kudoh T, et al. Nucleic Acids Symp Ser (Oxf). 2005;(49):25-6. doi: 10.1093/nass/49.1.25. Nucleic Acids Symp Ser (Oxf). 2005. PMID: 17150615

7

Synthesis of 5''-substituted cyclic ADP-carbocyclic-ribose as biological tools.

Sakaguchi N, Kudoh T, Murayama T, Arisawa M, Matsuda A, Shuto S. Sakaguchi N, et al. Among authors: kudoh t. Nucleic Acids Symp Ser (Oxf). 2006;(50):119-20. doi: 10.1093/nass/nrl059. Nucleic Acids Symp Ser (Oxf). 2006. PMID: 17150846

8

Substitution at the 8-position of 3''-deoxy-cyclic ADP-carbocyclic-ribose, a highly potent Ca2+-mobilizing agent, provides partial agonists.

Kudoh T, Murayama T, Matsuda A, Shuto S. Kudoh T, et al. Bioorg Med Chem. 2007 Apr 15;15(8):3032-40. doi: 10.1016/j.bmc.2007.02.001. Epub 2007 Feb 4. Bioorg Med Chem. 2007. PMID: 17317189

9

Synthesis of 5''-branched derivatives of cyclic ADP-carbocyclic-ribose, a potent Ca2+-mobilizing agent: The first antagonists modified at the N1-ribose moiety.

Sakaguchi N, Kudoh T, Tsuzuki T, Murayama T, Sakurai T, Matsuda A, Arisawa M, Shuto S. Sakaguchi N, et al. Among authors: kudoh t. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3814-8. doi: 10.1016/j.bmcl.2008.04.083. Epub 2008 May 20. Bioorg Med Chem Lett. 2008. PMID: 18534848

10

Synthesis and biological activity of cyclic ADP-carbocyclic-ribose and its analogs as stable mimics of Ca(2+)-mobilizing second messenger cyclic ADP-ribose.

Shuto S, Kudoh T, Fukuoka M, Ueno Y, Matsuda A. Shuto S, et al. Among authors: kudoh t. Nucleic Acids Res Suppl. 2001;(1):5-6. doi: 10.1093/nass/1.1.5. Nucleic Acids Res Suppl. 2001. PMID: 12836236

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