Spadafora C - Search Results

1

6-[1-(2,6-difluorophenyl)ethyl]pyrimidinones antagonize cell proliferation and induce cell differentiation by inhibiting (a nontelomeric) endogenous reverse transcriptase.

Bartolini S, Mai A, Artico M, Paesano N, Rotili D, Spadafora C, Sbardella G. Bartolini S, et al. Among authors: spadafora c. J Med Chem. 2005 Nov 3;48(22):6776-8. doi: 10.1021/jm0507330. J Med Chem. 2005. PMID: 16250634

2

6-alkylthio-4-[1-(2,6-difluorophenyl)alkyl]-1H-[1,3,5]triazin-2-ones (ADATs): novel regulators of cell differentiation and proliferation.

Sbardella G, Bartolini S, Castellano S, Artico M, Paesano N, Rotili D, Spadafora C, Mai A. Sbardella G, et al. Among authors: spadafora c. ChemMedChem. 2006 Oct;1(10):1073-80. doi: 10.1002/cmdc.200600139. ChemMedChem. 2006. PMID: 16944545

3

Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors.

Sbardella G, Mai A, Bartolini S, Castellano S, Cirilli R, Rotili D, Milite C, Santoriello M, Orlando S, Sciamanna I, Serafino A, Lavia P, Spadafora C. Sbardella G, et al. Among authors: spadafora c. J Med Chem. 2011 Aug 25;54(16):5927-36. doi: 10.1021/jm200734j. Epub 2011 Jul 22. J Med Chem. 2011. PMID: 21755950

4

Role of endogenous reverse transcriptase in murine early embryo development.

Pittoggi C, Sciamanna I, Mattei E, Beraldi R, Lobascio AM, Mai A, Quaglia MG, Lorenzini R, Spadafora C. Pittoggi C, et al. Among authors: spadafora c. Mol Reprod Dev. 2003 Nov;66(3):225-36. doi: 10.1002/mrd.10349. Mol Reprod Dev. 2003. PMID: 14502601

5

Reverse transcriptase inhibitors promote the remodelling of nuclear architecture and induce autophagy in prostate cancer cells.

Bellisai C, Sciamanna I, Rovella P, Giovannini D, Baranzini M, Pugliese GM, Zeya Ansari MS, Milite C, Sinibaldi-Vallebona P, Cirilli R, Sbardella G, Pichierri P, Trisciuoglio D, Lavia P, Serafino A, Spadafora C. Bellisai C, et al. Among authors: spadafora c. Cancer Lett. 2020 May 28;478:133-145. doi: 10.1016/j.canlet.2020.02.029. Epub 2020 Feb 26. Cancer Lett. 2020. PMID: 32112906

6

Endogenous reverse transcriptase: a mediator of cell proliferation and differentiation.

Spadafora C. Spadafora C. Cytogenet Genome Res. 2004;105(2-4):346-50. doi: 10.1159/000078207. Cytogenet Genome Res. 2004. PMID: 15237222 Review.

7

Inhibition of endogenous reverse transcriptase antagonizes human tumor growth.

Sciamanna I, Landriscina M, Pittoggi C, Quirino M, Mearelli C, Beraldi R, Mattei E, Serafino A, Cassano A, Sinibaldi-Vallebona P, Garaci E, Barone C, Spadafora C. Sciamanna I, et al. Among authors: spadafora c. Oncogene. 2005 Jun 2;24(24):3923-31. doi: 10.1038/sj.onc.1208562. Oncogene. 2005. PMID: 15806170

8

A tumor-promoting mechanism mediated by retrotransposon-encoded reverse transcriptase is active in human transformed cell lines.

Sciamanna I, Gualtieri A, Cossetti C, Osimo EF, Ferracin M, Macchia G, Aricò E, Prosseda G, Vitullo P, Misteli T, Spadafora C. Sciamanna I, et al. Among authors: spadafora c. Oncotarget. 2013 Dec;4(12):2271-87. doi: 10.18632/oncotarget.1403. Oncotarget. 2013. PMID: 24345856 Free PMC article.

9

Exposure of normal and transformed cells to nevirapine, a reverse transcriptase inhibitor, reduces cell growth and promotes differentiation.

Mangiacasale R, Pittoggi C, Sciamanna I, Careddu A, Mattei E, Lorenzini R, Travaglini L, Landriscina M, Barone C, Nervi C, Lavia P, Spadafora C. Mangiacasale R, et al. Among authors: spadafora c. Oncogene. 2003 May 8;22(18):2750-61. doi: 10.1038/sj.onc.1206354. Oncogene. 2003. PMID: 12747369

10

Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma.

Landriscina M, Fabiano A, Altamura S, Bagalà C, Piscazzi A, Cassano A, Spadafora C, Giorgino F, Barone C, Cignarelli M. Landriscina M, et al. Among authors: spadafora c. J Clin Endocrinol Metab. 2005 Oct;90(10):5663-71. doi: 10.1210/jc.2005-0367. Epub 2005 Jul 19. J Clin Endocrinol Metab. 2005. PMID: 16030158

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