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Page 1
Pyrrolo(iso)quinoline derivatives as 5-HT(2C) receptor agonists.
Adams DR, Bentley JM, Benwell KR, Bickerdike MJ, Bodkin CD, Cliffe IA, Dourish CT, George AR, Kennett GA, Knight AR, Malcolm CS, Mansell HL, Misra A, Quirk K, Roffey JR, Vickers SP. Adams DR, et al. Among authors: roffey jr. Bioorg Med Chem Lett. 2006 Feb;16(3):677-80. doi: 10.1016/j.bmcl.2005.10.029. Epub 2005 Oct 27. Bioorg Med Chem Lett. 2006. PMID: 16257207
Antagonists of the human adenosine A2A receptor. Part 3: Design and synthesis of pyrazolo[3,4-d]pyrimidines, pyrrolo[2,3-d]pyrimidines and 6-arylpurines.
Gillespie RJ, Cliffe IA, Dawson CE, Dourish CT, Gaur S, Jordan AM, Knight AR, Lerpiniere J, Misra A, Pratt RM, Roffey J, Stratton GC, Upton R, Weiss SM, Williamson DS. Gillespie RJ, et al. Bioorg Med Chem Lett. 2008 May 1;18(9):2924-9. doi: 10.1016/j.bmcl.2008.03.072. Epub 2008 Mar 30. Bioorg Med Chem Lett. 2008. PMID: 18411049
Indoline derivatives as 5-HT(2C) receptor agonists.
Bentley JM, Adams DR, Bebbington D, Benwell KR, Bickerdike MJ, Davidson JE, Dawson CE, Dourish CT, Duncton MA, Gaur S, George AR, Giles PR, Hamlyn RJ, Kennett GA, Knight AR, Malcolm CS, Mansell HL, Misra A, Monck NJ, Pratt RM, Quirk K, Roffey JR, Vickers SP, Cliffe IA. Bentley JM, et al. Among authors: roffey jr. Bioorg Med Chem Lett. 2004 May 3;14(9):2367-70. doi: 10.1016/j.bmcl.2003.05.001. Bioorg Med Chem Lett. 2004. PMID: 15081042
Synthesis and biological evaluation of novel hexahydro-pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazines as potent and selective 5-HT(2C) receptor agonists.
Richter HG, Adams DR, Benardeau A, Bickerdike MJ, Bentley JM, Blench TJ, Cliffe IA, Dourish C, Hebeisen P, Kennett GA, Knight AR, Malcolm CS, Mattei P, Misra A, Mizrahi J, Monck NJ, Plancher JM, Roever S, Roffey JR, Taylor S, Vickers SP. Richter HG, et al. Among authors: roffey jr. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1207-11. doi: 10.1016/j.bmcl.2005.11.083. Epub 2005 Dec 19. Bioorg Med Chem Lett. 2006. PMID: 16361098
Synthesis and cytotoxic activity of thiazolyl indolequinones.
Moody CJ, Roffey JR, Swann E, Lockyer S, Houlbrook S, Strafford IJ. Moody CJ, et al. Among authors: roffey jr. Anticancer Drugs. 1999 Jul;10(6):577-89. doi: 10.1097/00001813-199907000-00010. Anticancer Drugs. 1999. PMID: 10885906
Synthesis and cytotoxic activity of indolyl thiazoles.
Moody CJ, Roffey JR, Stephens MA, Stratford IJ. Moody CJ, et al. Among authors: roffey jr. Anticancer Drugs. 1997 Jun;8(5):489-99. doi: 10.1097/00001813-199706000-00012. Anticancer Drugs. 1997. PMID: 9215613