Ciruela A - Search Results

1

A direct interaction between the N terminus of adenylyl cyclase AC8 and the catalytic subunit of protein phosphatase 2A.

Crossthwaite AJ, Ciruela A, Rayner TF, Cooper DM. Crossthwaite AJ, et al. Among authors: ciruela a. Mol Pharmacol. 2006 Feb;69(2):608-17. doi: 10.1124/mol.105.018275. Epub 2005 Oct 28. Mol Pharmacol. 2006. PMID: 16258073

2

The cytosolic domains of Ca2+-sensitive adenylyl cyclases dictate their targeting to plasma membrane lipid rafts.

Crossthwaite AJ, Seebacher T, Masada N, Ciruela A, Dufraux K, Schultz JE, Cooper DM. Crossthwaite AJ, et al. Among authors: ciruela a. J Biol Chem. 2005 Feb 25;280(8):6380-91. doi: 10.1074/jbc.M411987200. Epub 2004 Dec 1. J Biol Chem. 2005. PMID: 15574428 Free article.

3

Localized Na+/H+ exchanger 1 expression protects Ca2+-regulated adenylyl cyclases from changes in intracellular pH.

Willoughby D, Masada N, Crossthwaite AJ, Ciruela A, Cooper DM. Willoughby D, et al. Among authors: ciruela a. J Biol Chem. 2005 Sep 2;280(35):30864-72. doi: 10.1074/jbc.M414355200. Epub 2005 Jul 7. J Biol Chem. 2005. PMID: 16002403 Free article.

4

The role of calmodulin recruitment in Ca2+ stimulation of adenylyl cyclase type 8.

Simpson RE, Ciruela A, Cooper DMF. Simpson RE, et al. Among authors: ciruela a. J Biol Chem. 2006 Jun 23;281(25):17379-17389. doi: 10.1074/jbc.M510992200. Epub 2006 Apr 13. J Biol Chem. 2006. PMID: 16613843 Free article.

5

Distinct mechanisms of regulation by Ca2+/calmodulin of type 1 and 8 adenylyl cyclases support their different physiological roles.

Masada N, Ciruela A, Macdougall DA, Cooper DM. Masada N, et al. Among authors: ciruela a. J Biol Chem. 2009 Feb 13;284(7):4451-63. doi: 10.1074/jbc.M807359200. Epub 2008 Nov 24. J Biol Chem. 2009. PMID: 19029295 Free PMC article.

6

Insights into the residence in lipid rafts of adenylyl cyclase AC8 and its regulation by capacitative calcium entry.

Pagano M, Clynes MA, Masada N, Ciruela A, Ayling LJ, Wachten S, Cooper DM. Pagano M, et al. Among authors: ciruela a. Am J Physiol Cell Physiol. 2009 Mar;296(3):C607-19. doi: 10.1152/ajpcell.00488.2008. Epub 2009 Jan 21. Am J Physiol Cell Physiol. 2009. PMID: 19158400 Free PMC article.

7

Capacitative Ca2+ entry via Orai1 and stromal interacting molecule 1 (STIM1) regulates adenylyl cyclase type 8.

Martin AC, Willoughby D, Ciruela A, Ayling LJ, Pagano M, Wachten S, Tengholm A, Cooper DM. Martin AC, et al. Among authors: ciruela a. Mol Pharmacol. 2009 Apr;75(4):830-42. doi: 10.1124/mol.108.051748. Epub 2009 Jan 26. Mol Pharmacol. 2009. PMID: 19171672 Free PMC article.

8

A key phosphorylation site in AC8 mediates regulation of Ca(2+)-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complex.

Willoughby D, Halls ML, Everett KL, Ciruela A, Skroblin P, Klussmann E, Cooper DM. Willoughby D, et al. Among authors: ciruela a. J Cell Sci. 2012 Dec 1;125(Pt 23):5850-9. doi: 10.1242/jcs.111427. Epub 2012 Sep 12. J Cell Sci. 2012. PMID: 22976297 Free PMC article.

9

Sustained entry of Ca2+ is required to activate Ca2+-calmodulin-dependent phosphodiesterase 1A.

Goraya TA, Masada N, Ciruela A, Cooper DM. Goraya TA, et al. Among authors: ciruela a. J Biol Chem. 2004 Sep 24;279(39):40494-504. doi: 10.1074/jbc.M313441200. Epub 2004 Jul 22. J Biol Chem. 2004. PMID: 15272012 Free article.

10

Dynamic regulation, desensitization, and cross-talk in discrete subcellular microdomains during beta2-adrenoceptor and prostanoid receptor cAMP signaling.

Willoughby D, Baillie GS, Lynch MJ, Ciruela A, Houslay MD, Cooper DM. Willoughby D, et al. Among authors: ciruela a. J Biol Chem. 2007 Nov 23;282(47):34235-49. doi: 10.1074/jbc.M706765200. Epub 2007 Sep 13. J Biol Chem. 2007. PMID: 17855344 Free article.

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