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Induction of protective serum meningococcal bactericidal and diphtheria-neutralizing antibodies and mucosal immunoglobulin A in volunteers by nasal insufflations of the Neisseria meningitidis serogroup C polysaccharide-CRM197 conjugate vaccine mixed with chitosan.
Huo Z, Sinha R, McNeela EA, Borrow R, Giemza R, Cosgrove C, Heath PT, Mills KH, Rappuoli R, Griffin GE, Lewis DJ. Huo Z, et al. Among authors: rappuoli r. Infect Immun. 2005 Dec;73(12):8256-65. doi: 10.1128/IAI.73.12.8256-8265.2005. Infect Immun. 2005. PMID: 16299322 Free PMC article. Clinical Trial.
Mutants of Escherichia coli heat-labile toxin act as effective mucosal adjuvants for nasal delivery of an acellular pertussis vaccine: differential effects of the nontoxic AB complex and enzyme activity on Th1 and Th2 cells.
Ryan EJ, McNeela E, Murphy GA, Stewart H, O'hagan D, Pizza M, Rappuoli R, Mills KH. Ryan EJ, et al. Among authors: rappuoli r. Infect Immun. 1999 Dec;67(12):6270-80. doi: 10.1128/IAI.67.12.6270-6280.1999. Infect Immun. 1999. PMID: 10569737 Free PMC article.
Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.
Miyaji EN, Mazzantini RP, Dias WO, Nascimento AL, Marcovistz R, Matos DS, Raw I, Winter N, Gicquel B, Rappuoli R, Leite LC. Miyaji EN, et al. Among authors: rappuoli r. Infect Immun. 2001 Feb;69(2):869-74. doi: 10.1128/IAI.69.2.869-874.2001. Infect Immun. 2001. PMID: 11159980 Free PMC article.
820 results