Hutchinson CR - Search Results

1

Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus.

Wendt-Pienkowski E, Huang Y, Zhang J, Li B, Jiang H, Kwon H, Hutchinson CR, Shen B. Wendt-Pienkowski E, et al. Among authors: hutchinson cr. J Am Chem Soc. 2005 Nov 30;127(47):16442-52. doi: 10.1021/ja054376u. J Am Chem Soc. 2005. PMID: 16305230

2

Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production.

Summers RG, Donadio S, Staver MJ, Wendt-Pienkowski E, Hutchinson CR, Katz L. Summers RG, et al. Among authors: hutchinson cr. Microbiology (Reading). 1997 Oct;143 ( Pt 10):3251-3262. doi: 10.1099/00221287-143-10-3251. Microbiology (Reading). 1997. PMID: 9353926 Free article.

3

Feedback regulation of doxorubicin biosynthesis in Streptomyces peucetius.

Jiang H, Hutchinson CR. Jiang H, et al. Among authors: hutchinson cr. Res Microbiol. 2006 Sep;157(7):666-74. doi: 10.1016/j.resmic.2006.02.004. Epub 2006 Mar 3. Res Microbiol. 2006. PMID: 16545946 Free article.

4

Nucleotide sequence of the tcmII-tcmIV region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens and evidence that the tcmN gene encodes a multifunctional cyclase-dehydratase-O-methyl transferase.

Summers RG, Wendt-Pienkowski E, Motamedi H, Hutchinson CR. Summers RG, et al. Among authors: hutchinson cr. J Bacteriol. 1992 Mar;174(6):1810-20. doi: 10.1128/jb.174.6.1810-1820.1992. J Bacteriol. 1992. PMID: 1548230 Free PMC article.

5

Triple hydroxylation of tetracenomycin A2 to tetracenomycin C in Streptomyces glaucescens. Overexpression of the tcmG gene in Streptomyces lividans and characterization of the tetracenomycin A2 oxygenase.

Shen B, Hutchinson CR. Shen B, et al. Among authors: hutchinson cr. J Biol Chem. 1994 Dec 2;269(48):30726-33. J Biol Chem. 1994. PMID: 7982994 Free article.

6

Tetracenomycin F2 cyclase: intramolecular aldol condensation in the biosynthesis of tetracenomycin C in Streptomyces glaucescens.

Shen B, Hutchinson CR. Shen B, et al. Among authors: hutchinson cr. Biochemistry. 1993 Oct 19;32(41):11149-54. doi: 10.1021/bi00092a026. Biochemistry. 1993. PMID: 8218177

7

The tcmVI region of the tetracenomycin C biosynthetic gene cluster of Streptomyces glaucescens encodes the tetracenomycin F1 monooxygenase, tetracenomycin F2 cyclase, and, most likely, a second cyclase.

Summers RG, Wendt-Pienkowski E, Motamedi H, Hutchinson CR. Summers RG, et al. Among authors: hutchinson cr. J Bacteriol. 1993 Dec;175(23):7571-80. doi: 10.1128/jb.175.23.7571-7580.1993. J Bacteriol. 1993. PMID: 8244926 Free PMC article.

8

Enzymatic synthesis of a bacterial polyketide from acetyl and malonyl coenzyme A.

Shen B, Hutchinson CR. Shen B, et al. Among authors: hutchinson cr. Science. 1993 Dec 3;262(5139):1535-40. doi: 10.1126/science.8248801. Science. 1993. PMID: 8248801

9

Tetracenomycin F1 monooxygenase: oxidation of a naphthacenone to a naphthacenequinone in the biosynthesis of tetracenomycin C in Streptomyces glaucescens.

Shen B, Hutchinson CR. Shen B, et al. Among authors: hutchinson cr. Biochemistry. 1993 Jul 6;32(26):6656-63. doi: 10.1021/bi00077a019. Biochemistry. 1993. PMID: 8329392

10

Deciphering the mechanism for the assembly of aromatic polyketides by a bacterial polyketide synthase.

Shen B, Hutchinson CR. Shen B, et al. Among authors: hutchinson cr. Proc Natl Acad Sci U S A. 1996 Jun 25;93(13):6600-4. doi: 10.1073/pnas.93.13.6600. Proc Natl Acad Sci U S A. 1996. PMID: 8692863 Free PMC article.

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