Berghuis AM - Search Results

1

Crystal structure of homoserine transacetylase from Haemophilus influenzae reveals a new family of alpha/beta-hydrolases.

Mirza IA, Nazi I, Korczynska M, Wright GD, Berghuis AM. Mirza IA, et al. Among authors: berghuis am. Biochemistry. 2005 Dec 6;44(48):15768-73. doi: 10.1021/bi051951y. Biochemistry. 2005. PMID: 16313180

2

Structural basis for streptogramin B resistance in Staphylococcus aureus by virginiamycin B lyase.

Korczynska M, Mukhtar TA, Wright GD, Berghuis AM. Korczynska M, et al. Among authors: berghuis am. Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10388-93. doi: 10.1073/pnas.0701809104. Epub 2007 Jun 11. Proc Natl Acad Sci U S A. 2007. PMID: 17563376 Free PMC article.

3

Mechanism of aminoglycoside antibiotic kinase APH(3')-IIIa: role of the nucleotide positioning loop.

Thompson PR, Boehr DD, Berghuis AM, Wright GD. Thompson PR, et al. Among authors: berghuis am. Biochemistry. 2002 Jun 4;41(22):7001-7. doi: 10.1021/bi0256680. Biochemistry. 2002. PMID: 12033933

4

Enzyme-assisted suicide: molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase.

Jacques SL, Mirza IA, Ejim L, Koteva K, Hughes DW, Green K, Kinach R, Honek JF, Lai HK, Berghuis AM, Wright GD. Jacques SL, et al. Among authors: berghuis am. Chem Biol. 2003 Oct;10(10):989-95. doi: 10.1016/j.chembiol.2003.09.015. Chem Biol. 2003. PMID: 14583265

5

New phenolic inhibitors of yeast homoserine dehydrogenase.

Ejim L, Mirza IA, Capone C, Nazi I, Jenkins S, Chee GL, Berghuis AM, Wright GD. Ejim L, et al. Among authors: berghuis am. Bioorg Med Chem. 2004 Jul 15;12(14):3825-30. doi: 10.1016/j.bmc.2004.05.009. Bioorg Med Chem. 2004. PMID: 15210149

6

Magnesium and phosphate ions enable NAD binding to methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase.

Christensen KE, Mirza IA, Berghuis AM, Mackenzie RE. Christensen KE, et al. Among authors: berghuis am. J Biol Chem. 2005 Oct 7;280(40):34316-23. doi: 10.1074/jbc.M505210200. Epub 2005 Aug 11. J Biol Chem. 2005. PMID: 16100107 Free article.

7

Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b.

Peschard P, Kozlov G, Lin T, Mirza IA, Berghuis AM, Lipkowitz S, Park M, Gehring K. Peschard P, et al. Among authors: berghuis am. Mol Cell. 2007 Aug 3;27(3):474-85. doi: 10.1016/j.molcel.2007.06.023. Mol Cell. 2007. PMID: 17679095 Free article.

8

Crystal structures of cyclohexanone monooxygenase reveal complex domain movements and a sliding cofactor.

Mirza IA, Yachnin BJ, Wang S, Grosse S, Bergeron H, Imura A, Iwaki H, Hasegawa Y, Lau PC, Berghuis AM. Mirza IA, et al. Among authors: berghuis am. J Am Chem Soc. 2009 Jul 1;131(25):8848-54. doi: 10.1021/ja9010578. J Am Chem Soc. 2009. PMID: 19385644

9

Crystal structure of an aminoglycoside 6'-N-acetyltransferase: defining the GCN5-related N-acetyltransferase superfamily fold.

Wybenga-Groot LE, Draker K, Wright GD, Berghuis AM. Wybenga-Groot LE, et al. Among authors: berghuis am. Structure. 1999 May;7(5):497-507. doi: 10.1016/s0969-2126(99)80066-5. Structure. 1999. PMID: 10378269 Free article.

10

Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases.

DeLaBarre B, Thompson PR, Wright GD, Berghuis AM. DeLaBarre B, et al. Among authors: berghuis am. Nat Struct Biol. 2000 Mar;7(3):238-44. doi: 10.1038/73359. Nat Struct Biol. 2000. PMID: 10700284

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