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Page 1
Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia.
Kröber A, Bloehdorn J, Hafner S, Bühler A, Seiler T, Kienle D, Winkler D, Bangerter M, Schlenk RF, Benner A, Lichter P, Döhner H, Stilgenbauer S. Kröber A, et al. Among authors: winkler d. J Clin Oncol. 2006 Feb 20;24(6):969-75. doi: 10.1200/JCO.2005.03.7184. Epub 2006 Jan 17. J Clin Oncol. 2006. PMID: 16418492
Clonal evolution in chronic lymphocytic leukemia: acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival.
Stilgenbauer S, Sander S, Bullinger L, Benner A, Leupolt E, Winkler D, Kröber A, Kienle D, Lichter P, Döhner H. Stilgenbauer S, et al. Among authors: winkler d. Haematologica. 2007 Sep;92(9):1242-5. doi: 10.3324/haematol.10720. Epub 2007 Aug 1. Haematologica. 2007. PMID: 17666364 Free article.
Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up.
Zenz T, Kröber A, Scherer K, Häbe S, Bühler A, Benner A, Denzel T, Winkler D, Edelmann J, Schwänen C, Döhner H, Stilgenbauer S. Zenz T, et al. Among authors: winkler d. Blood. 2008 Oct 15;112(8):3322-9. doi: 10.1182/blood-2008-04-154070. Epub 2008 Aug 8. Blood. 2008. PMID: 18689542 Free article.
miR-34a as part of the resistance network in chronic lymphocytic leukemia.
Zenz T, Mohr J, Eldering E, Kater AP, Bühler A, Kienle D, Winkler D, Dürig J, van Oers MH, Mertens D, Döhner H, Stilgenbauer S. Zenz T, et al. Among authors: winkler d. Blood. 2009 Apr 16;113(16):3801-8. doi: 10.1182/blood-2008-08-172254. Epub 2008 Oct 21. Blood. 2009. PMID: 18941118 Free article.
Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial.
Zenz T, Häbe S, Denzel T, Mohr J, Winkler D, Bühler A, Sarno A, Groner S, Mertens D, Busch R, Hallek M, Döhner H, Stilgenbauer S. Zenz T, et al. Among authors: winkler d. Blood. 2009 Sep 24;114(13):2589-97. doi: 10.1182/blood-2009-05-224071. Epub 2009 Jul 30. Blood. 2009. PMID: 19643983 Free article. Clinical Trial.
A novel paradigm to trigger apoptosis in chronic lymphocytic leukemia.
Loeder S, Zenz T, Schnaiter A, Mertens D, Winkler D, Döhner H, Debatin KM, Stilgenbauer S, Fulda S. Loeder S, et al. Among authors: winkler d. Cancer Res. 2009 Dec 1;69(23):8977-86. doi: 10.1158/0008-5472.CAN-09-2604. Epub 2009 Nov 17. Cancer Res. 2009. PMID: 19920200
Protein expression analysis of chronic lymphocytic leukemia defines the effect of genetic aberrations and uncovers a correlation of CDK4, P27 and P53 with hierarchical risk.
Winkler D, Schneider C, Zucknick M, Bögelein D, Schulze K, Zenz T, Mohr J, Philippen A, Huber H, Bühler A, Habermann A, Benner A, Döhner H, Stilgenbauer S, Mertens D. Winkler D, et al. Haematologica. 2010 Nov;95(11):1880-8. doi: 10.3324/haematol.2010.025734. Epub 2010 Aug 16. Haematologica. 2010. PMID: 20713460 Free PMC article.
839 results