Rycroft W - Search Results

1

An inverse agonist selective for alpha5 subunit-containing GABAA receptors enhances cognition.

Dawson GR, Maubach KA, Collinson N, Cobain M, Everitt BJ, MacLeod AM, Choudhury HI, McDonald LM, Pillai G, Rycroft W, Smith AJ, Sternfeld F, Tattersall FD, Wafford KA, Reynolds DS, Seabrook GR, Atack JR. Dawson GR, et al. Among authors: rycroft w. J Pharmacol Exp Ther. 2006 Mar;316(3):1335-45. doi: 10.1124/jpet.105.092320. Epub 2005 Dec 2. J Pharmacol Exp Ther. 2006. PMID: 16326923

2

An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties.

Chambers MS, Atack JR, Carling RW, Collinson N, Cook SM, Dawson GR, Ferris P, Hobbs SC, O'connor D, Marshall G, Rycroft W, Macleod AM. Chambers MS, et al. Among authors: rycroft w. J Med Chem. 2004 Nov 18;47(24):5829-32. doi: 10.1021/jm040863t. J Med Chem. 2004. PMID: 15537339

3

Enantioselective inhibition of apomorphine-induced emesis in the ferret by the neurokinin1 receptor antagonist CP-99,994.

Tattersall FD, Rycroft W, Hill RG, Hargreaves RJ. Tattersall FD, et al. Among authors: rycroft w. Neuropharmacology. 1994 Feb;33(2):259-60. doi: 10.1016/0028-3908(94)90018-3. Neuropharmacology. 1994. PMID: 8035913

4

The behavioral effects of heptyl physostigmine, a new cholinesterase inhibitor, in tests of long-term and working memory in rodents.

Dawson GR, Bentley G, Draper F, Rycroft W, Iversen SD, Pagella PG. Dawson GR, et al. Among authors: rycroft w. Pharmacol Biochem Behav. 1991 Aug;39(4):865-71. doi: 10.1016/0091-3057(91)90045-4. Pharmacol Biochem Behav. 1991. PMID: 1763105

5

The tachykinin NK1 receptor antagonist CP-99,994 attenuates cisplatin induced emesis in the ferret.

Tattersall FD, Rycroft W, Hargreaves RJ, Hill RG. Tattersall FD, et al. Among authors: rycroft w. Eur J Pharmacol. 1993 Nov 30;250(1):R5-6. doi: 10.1016/0014-2999(93)90649-3. Eur J Pharmacol. 1993. PMID: 8119305

6

Enantiospecific inhibition of emesis induced by nicotine in the house musk shrew (Suncus murinus) by the neurokinin1 (NK1) receptor antagonist CP-99,994.

Tattersall FD, Rycroft W, Marmont N, Cascieri M, Hill RG, Hargreaves RJ. Tattersall FD, et al. Among authors: rycroft w. Neuropharmacology. 1995 Dec;34(12):1697-9. doi: 10.1016/0028-3908(95)00164-6. Neuropharmacology. 1995. PMID: 8788968

7

Tachykinin NK1 receptor antagonists act centrally to inhibit emesis induced by the chemotherapeutic agent cisplatin in ferrets.

Tattersall FD, Rycroft W, Francis B, Pearce D, Merchant K, MacLeod AM, Ladduwahetty T, Keown L, Swain C, Baker R, Cascieri M, Ber E, Metzger J, MacIntyre DE, Hill RG, Hargreaves RJ. Tattersall FD, et al. Among authors: rycroft w. Neuropharmacology. 1996;35(8):1121-9. doi: 10.1016/s0028-3908(96)00020-2. Neuropharmacology. 1996. PMID: 9121615

8

In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists.

Rupniak NM, Tattersall FD, Williams AR, Rycroft W, Carlson EJ, Cascieri MA, Sadowski S, Ber E, Hale JJ, Mills SG, MacCoss M, Seward E, Huscroft I, Owen S, Swain CJ, Hill RG, Hargreaves RJ. Rupniak NM, et al. Among authors: rycroft w. Eur J Pharmacol. 1997 May 20;326(2-3):201-9. doi: 10.1016/s0014-2999(97)85415-5. Eur J Pharmacol. 1997. PMID: 9196273

9

The novel NK1 receptor antagonist MK-0869 (L-754,030) and its water soluble phosphoryl prodrug, L-758,298, inhibit acute and delayed cisplatin-induced emesis in ferrets.

Tattersall FD, Rycroft W, Cumberbatch M, Mason G, Tye S, Williamson DJ, Hale JJ, Mills SG, Finke PE, MacCoss M, Sadowski S, Ber E, Cascieri M, Hill RG, MacIntyre DE, Hargreaves RJ. Tattersall FD, et al. Among authors: rycroft w. Neuropharmacology. 2000 Feb 14;39(4):652-63. doi: 10.1016/s0028-3908(99)00172-0. Neuropharmacology. 2000. PMID: 10728886

10

Phosphorylated morpholine acetal human neurokinin-1 receptor antagonists as water-soluble prodrugs.

Hale JJ, Mills SG, MacCoss M, Dorn CP, Finke PE, Budhu RJ, Reamer RA, Huskey SE, Luffer-Atlas D, Dean BJ, McGowan EM, Feeney WP, Chiu SH, Cascieri MA, Chicchi GG, Kurtz MM, Sadowski S, Ber E, Tattersall FD, Rupniak NM, Williams AR, Rycroft W, Hargreaves R, Metzger JM, MacIntyre DE. Hale JJ, et al. Among authors: rycroft w. J Med Chem. 2000 Mar 23;43(6):1234-41. doi: 10.1021/jm990617v. J Med Chem. 2000. PMID: 10737756

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