Carden MJ - Search Results

1

The cold-shock response in cultured mammalian cells: harnessing the response for the improvement of recombinant protein production.

Al-Fageeh MB, Marchant RJ, Carden MJ, Smales CM. Al-Fageeh MB, et al. Among authors: carden mj. Biotechnol Bioeng. 2006 Apr 5;93(5):829-35. doi: 10.1002/bit.20789. Biotechnol Bioeng. 2006. PMID: 16329142 Review.

2

Biochemical insights into the mechanisms central to the response of mammalian cells to cold stress and subsequent rewarming.

Roobol A, Carden MJ, Newsam RJ, Smales CM. Roobol A, et al. Among authors: carden mj. FEBS J. 2009 Jan;276(1):286-302. doi: 10.1111/j.1742-4658.2008.06781.x. Epub 2008 Nov 28. FEBS J. 2009. PMID: 19054067 Free article.

3

Post-translational events of a model reporter protein proceed with higher fidelity and accuracy upon mild hypothermic culturing of Chinese hamster ovary cells.

Masterton RJ, Roobol A, Al-Fageeh MB, Carden MJ, Smales CM. Masterton RJ, et al. Among authors: carden mj. Biotechnol Bioeng. 2010 Jan 1;105(1):215-20. doi: 10.1002/bit.22533. Biotechnol Bioeng. 2010. PMID: 19739092

4

ATR (ataxia telangiectasia mutated- and Rad3-related kinase) is activated by mild hypothermia in mammalian cells and subsequently activates p53.

Roobol A, Roobol J, Carden MJ, Bastide A, Willis AE, Dunn WB, Goodacre R, Smales CM. Roobol A, et al. Among authors: carden mj. Biochem J. 2011 Apr 15;435(2):499-508. doi: 10.1042/BJ20101303. Biochem J. 2011. PMID: 21284603

5

On the effect of transient expression of mutated eIF2alpha and eIF4E eukaryotic translation initiation factors on reporter gene expression in mammalian cells upon cold-shock.

Underhill MF, Marchant RJ, Carden MJ, James DC, Smales CM. Underhill MF, et al. Among authors: carden mj. Mol Biotechnol. 2006 Oct;34(2):141-9. doi: 10.1385/mb:34:2:141. Mol Biotechnol. 2006. PMID: 17172659

6

Modulation of phosducin-like protein 3 (PhLP3) levels promotes cytoskeletal remodelling in a MAPK and RhoA-dependent manner.

Hayes NV, Jossé L, Smales CM, Carden MJ. Hayes NV, et al. Among authors: carden mj. PLoS One. 2011;6(12):e28271. doi: 10.1371/journal.pone.0028271. Epub 2011 Dec 9. PLoS One. 2011. PMID: 22174782 Free PMC article.

7

The chaperonin CCT interacts with and mediates the correct folding and activity of three subunits of translation initiation factor eIF3: b, i and h.

Roobol A, Roobol J, Carden MJ, Smith ME, Hershey JW, Bastide A, Knight JR, Willis AE, Smales CM. Roobol A, et al. Among authors: carden mj. Biochem J. 2014 Mar 1;458(2):213-24. doi: 10.1042/BJ20130979. Biochem J. 2014. PMID: 24320561

8

Engineered transient and stable overexpression of translation factors eIF3i and eIF3c in CHOK1 and HEK293 cells gives enhanced cell growth associated with increased c-Myc expression and increased recombinant protein synthesis.

Roobol A, Roobol J, Smith ME, Carden MJ, Hershey JWB, Willis AE, Smales CM. Roobol A, et al. Among authors: carden mj. Metab Eng. 2020 May;59:98-105. doi: 10.1016/j.ymben.2020.02.001. Epub 2020 Feb 13. Metab Eng. 2020. PMID: 32061967 Free PMC article.

9

Molecular characterisation of a novel, repetitive protein of the paraflagellar rod in Trypanosoma brucei.

Woodward R, Carden MJ, Gull K. Woodward R, et al. Among authors: carden mj. Mol Biochem Parasitol. 1994 Sep;67(1):31-9. doi: 10.1016/0166-6851(94)90093-0. Mol Biochem Parasitol. 1994. PMID: 7838181

10

Subunits of the eukaryotic cytosolic chaperonin CCT do not always behave as components of a uniform hetero-oligomeric particle.

Roobol A, Carden MJ. Roobol A, et al. Among authors: carden mj. Eur J Cell Biol. 1999 Jan;78(1):21-32. doi: 10.1016/S0171-9335(99)80004-1. Eur J Cell Biol. 1999. PMID: 10082421

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