Reddy JA - Search Results

1

Folate receptor specific anti-tumor activity of folate-mitomycin conjugates.

Reddy JA, Westrick E, Vlahov I, Howard SJ, Santhapuram HK, Leamon CP. Reddy JA, et al. Cancer Chemother Pharmacol. 2006 Aug;58(2):229-36. doi: 10.1007/s00280-005-0151-z. Epub 2005 Dec 6. Cancer Chemother Pharmacol. 2006. PMID: 16331500

2

Design and synthesis of a folate-receptor targeted diazepine-ring-opened pyrrolobenzodiazepine prodrug conjugate.

Vlahov IR, Qi L, Santhapuram HKR, Felten A, Parham GL, Zou N, Wang K, You F, Vaughn JF, Hahn SJ, Klein HF, Kleindl PJ, Reddy J, Reno D, Nicoson J, Leamon CP. Vlahov IR, et al. Bioorg Med Chem Lett. 2020 Apr 1;30(7):126987. doi: 10.1016/j.bmcl.2020.126987. Epub 2020 Jan 27. Bioorg Med Chem Lett. 2020. PMID: 32029324

3

Ligand binding and kinetics of folate receptor recycling in vivo: impact on receptor-mediated drug delivery.

Paulos CM, Reddy JA, Leamon CP, Turk MJ, Low PS. Paulos CM, et al. Among authors: reddy ja. Mol Pharmacol. 2004 Dec;66(6):1406-14. doi: 10.1124/mol.104.003723. Epub 2004 Sep 15. Mol Pharmacol. 2004. PMID: 15371560

4

Synthesis and biological evaluation of EC72: a new folate-targeted chemotherapeutic.

Leamon CP, Reddy JA, Vlahov IR, Vetzel M, Parker N, Nicoson JS, Xu LC, Westrick E. Leamon CP, et al. Among authors: reddy ja. Bioconjug Chem. 2005 Jul-Aug;16(4):803-11. doi: 10.1021/bc049709b. Bioconjug Chem. 2005. PMID: 16029021

5

Synthesis and biological evaluation of EC140: a novel folate-targeted vinca alkaloid conjugate.

Leamon CP, Reddy JA, Vlahov IR, Kleindl PJ, Vetzel M, Westrick E. Leamon CP, et al. Among authors: reddy ja. Bioconjug Chem. 2006 Sep-Oct;17(5):1226-32. doi: 10.1021/bc060145g. Bioconjug Chem. 2006. PMID: 16984132

6

Preclinical pharmacokinetics, tissue distribution, and antitumor activity of a folate-hapten conjugate-targeted immunotherapy in hapten-immunized mice.

Lu Y, Xu LC, Parker N, Westrick E, Reddy JA, Vetzel M, Low PS, Leamon CP. Lu Y, et al. Among authors: reddy ja. Mol Cancer Ther. 2006 Dec;5(12):3258-67. doi: 10.1158/1535-7163.MCT-06-0439. Mol Cancer Ther. 2006. PMID: 17172429

7

Preclinical evaluation of EC145, a folate-vinca alkaloid conjugate.

Reddy JA, Dorton R, Westrick E, Dawson A, Smith T, Xu LC, Vetzel M, Kleindl P, Vlahov IR, Leamon CP. Reddy JA, et al. Cancer Res. 2007 May 1;67(9):4434-42. doi: 10.1158/0008-5472.CAN-07-0033. Cancer Res. 2007. PMID: 17483358

8

Comparative preclinical activity of the folate-targeted Vinca alkaloid conjugates EC140 and EC145.

Leamon CP, Reddy JA, Vlahov IR, Westrick E, Parker N, Nicoson JS, Vetzel M. Leamon CP, et al. Among authors: reddy ja. Int J Cancer. 2007 Oct 1;121(7):1585-92. doi: 10.1002/ijc.22853. Int J Cancer. 2007. PMID: 17551919

9

Folate receptor-specific antitumor activity of EC131, a folate-maytansinoid conjugate.

Reddy JA, Westrick E, Santhapuram HK, Howard SJ, Miller ML, Vetzel M, Vlahov I, Chari RV, Goldmacher VS, Leamon CP. Reddy JA, et al. Cancer Res. 2007 Jul 1;67(13):6376-82. doi: 10.1158/0008-5472.CAN-06-3894. Cancer Res. 2007. PMID: 17616697

10

Preclinical antitumor activity of a novel folate-targeted dual drug conjugate.

Leamon CP, Reddy JA, Vlahov IR, Westrick E, Dawson A, Dorton R, Vetzel M, Santhapuram HK, Wang Y. Leamon CP, et al. Among authors: reddy ja. Mol Pharm. 2007 Sep-Oct;4(5):659-67. doi: 10.1021/mp070049c. Epub 2007 Sep 18. Mol Pharm. 2007. PMID: 17874843

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