Stanton JA - Search Results

1

Aminoalkyl phenyl sulfones--a novel series of 5-HT7 receptor ligands.

Raubo P, Beer MS, Hunt PA, Huscroft IT, London C, Stanton JA, Kulagowski JJ. Raubo P, et al. Among authors: stanton ja. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1255-8. doi: 10.1016/j.bmcl.2005.11.067. Epub 2005 Dec 7. Bioorg Med Chem Lett. 2006. PMID: 16337790

2

Synthesis and serotonergic activity of 3-[2-(pyrrolidin-1-yl)ethyl]indoles: potent agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B receptor.

Sternfeld F, Guiblin AR, Jelley RA, Matassa VG, Reeve AJ, Hunt PA, Beer MS, Heald A, Stanton JA, Sohal B, Watt AP, Street LJ. Sternfeld F, et al. Among authors: stanton ja. J Med Chem. 1999 Feb 25;42(4):677-90. doi: 10.1021/jm9805687. J Med Chem. 1999. PMID: 10052975

3

3-(Piperazinylpropyl)indoles: selective, orally bioavailable h5-HT1D receptor agonists as potential antimigraine agents.

Chambers MS, Street LJ, Goodacre S, Hobbs SC, Hunt P, Jelley RA, Matassa VG, Reeve AJ, Sternfeld F, Beer MS, Stanton JA, Rathbone D, Watt AP, MacLeod AM. Chambers MS, et al. Among authors: stanton ja. J Med Chem. 1999 Feb 25;42(4):691-705. doi: 10.1021/jm980569z. J Med Chem. 1999. PMID: 10052976

4

Fluorination of 3-(3-(piperidin-1-yl)propyl)indoles and 3-(3-(piperazin-1-yl)propyl)indoles gives selective human 5-HT1D receptor ligands with improved pharmacokinetic profiles.

van Niel MB, Collins I, Beer MS, Broughton HB, Cheng SK, Goodacre SC, Heald A, Locker KL, MacLeod AM, Morrison D, Moyes CR, O'Connor D, Pike A, Rowley M, Russell MG, Sohal B, Stanton JA, Thomas S, Verrier H, Watt AP, Castro JL. van Niel MB, et al. Among authors: stanton ja. J Med Chem. 1999 Jun 17;42(12):2087-104. doi: 10.1021/jm981133m. J Med Chem. 1999. PMID: 10377215

5

3-[3-(Piperidin-1-yl)propyl]indoles as highly selective h5-HT(1D) receptor agonists.

Russell MG, Matassa VG, Pengilley RR, van Niel MB, Sohal B, Watt AP, Hitzel L, Beer MS, Stanton JA, Broughton HB, Castro JL. Russell MG, et al. Among authors: stanton ja. J Med Chem. 1999 Dec 2;42(24):4981-5001. doi: 10.1021/jm9910021. J Med Chem. 1999. PMID: 10585208

6

Novel 5-HT3 antagonists: indol-3-ylspiro(azabicycloalkane-3,5'(4'H)-oxazoles).

Swain CJ, Baker R, Kneen C, Herbert R, Moseley J, Saunders J, Seward EM, Stevenson GI, Beer M, Stanton J, et al. Swain CJ, et al. J Med Chem. 1992 Mar 20;35(6):1019-31. doi: 10.1021/jm00084a007. J Med Chem. 1992. PMID: 1552497

7

Novel 5-HT3 antagonists. Indole oxadiazoles.

Swain CJ, Baker R, Kneen C, Moseley J, Saunders J, Seward EM, Stevenson G, Beer M, Stanton J, Watling K. Swain CJ, et al. J Med Chem. 1991 Jan;34(1):140-51. doi: 10.1021/jm00105a021. J Med Chem. 1991. PMID: 1992112

8

Synthesis and biological activity of 3-[2-(dimethylamino)ethyl]-5-[(1,1-dioxo-5-methyl-1,2,5-thiadiazolidin- 2-yl)-methyl]-1H-indole and analogues: agonists for the 5-HT1D receptor.

Castro JL, Baker R, Guiblin AR, Hobbs SC, Jenkins MR, Russell MG, Beer MS, Stanton JA, Scholey K, Hargreaves RJ, et al. Castro JL, et al. Among authors: stanton ja. J Med Chem. 1994 Sep 16;37(19):3023-32. doi: 10.1021/jm00045a006. J Med Chem. 1994. PMID: 7932524

9

Characterisation of a cloned human 5-HT1A receptor cell line using [35S]GTP gamma S binding.

Stanton JA, Beer MS. Stanton JA, et al. Eur J Pharmacol. 1997 Feb 12;320(2-3):267-75. doi: 10.1016/s0014-2999(96)00914-4. Eur J Pharmacol. 1997. PMID: 9059863

10

3-[2-(Pyrrolidin-1-yl)ethyl]indoles and 3-[3-(piperidin-1-yl)propyl]indoles: agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B subtype.

Castro JL, Street LJ, Guiblin AR, Jelley RA, Russell MG, Sternfeld F, Beer MS, Stanton JA, Matassa VG. Castro JL, et al. Among authors: stanton ja. J Med Chem. 1997 Oct 24;40(22):3497-500. doi: 10.1021/jm9704558. J Med Chem. 1997. PMID: 9357514 No abstract available.

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