Cheng GZ - Search Results

1

Targeting the phosphatidylinositol-3 kinase/Akt pathway for the treatment of cancer.

Kim D, Cheng GZ, Lindsley CW, Yang H, Cheng JQ. Kim D, et al. Among authors: cheng gz, cheng jq. Curr Opin Investig Drugs. 2005 Dec;6(12):1250-8. Curr Opin Investig Drugs. 2005. PMID: 16370391 Review.

2

The Akt/PKB pathway: molecular target for cancer drug discovery.

Cheng JQ, Lindsley CW, Cheng GZ, Yang H, Nicosia SV. Cheng JQ, et al. Among authors: cheng gz. Oncogene. 2005 Nov 14;24(50):7482-92. doi: 10.1038/sj.onc.1209088. Oncogene. 2005. PMID: 16288295 Review.

3

Advances of AKT pathway in human oncogenesis and as a target for anti-cancer drug discovery.

Cheng GZ, Park S, Shu S, He L, Kong W, Zhang W, Yuan Z, Wang LH, Cheng JQ. Cheng GZ, et al. Among authors: cheng jq. Curr Cancer Drug Targets. 2008 Feb;8(1):2-6. Curr Cancer Drug Targets. 2008. PMID: 18288938 Review.

4

Akt attenuation of the serine protease activity of HtrA2/Omi through phosphorylation of serine 212.

Yang L, Sun M, Sun XM, Cheng GZ, Nicosia SV, Cheng JQ. Yang L, et al. Among authors: cheng gz, cheng jq. J Biol Chem. 2007 Apr 13;282(15):10981-7. doi: 10.1074/jbc.M700445200. Epub 2007 Feb 20. J Biol Chem. 2007. Retraction in: J Biol Chem. 2016 Oct 21;291(43):22843. doi: 10.1074/jbc.A116.700445 PMID: 17311912 Free article. Retracted.

5

Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function.

Cheng GZ, Zhang WZ, Sun M, Wang Q, Coppola D, Mansour M, Xu LM, Costanzo C, Cheng JQ, Wang LH. Cheng GZ, et al. Among authors: cheng jq. J Biol Chem. 2008 May 23;283(21):14665-73. doi: 10.1074/jbc.M707429200. Epub 2008 Mar 19. J Biol Chem. 2008. PMID: 18353781 Free PMC article.

6

RACK1 and CIS mediate the degradation of BimEL in cancer cells.

Zhang W, Cheng GZ, Gong J, Hermanto U, Zong CS, Chan J, Cheng JQ, Wang LH. Zhang W, et al. Among authors: cheng gz, cheng jq. J Biol Chem. 2008 Jun 13;283(24):16416-26. doi: 10.1074/jbc.M802360200. Epub 2008 Apr 17. J Biol Chem. 2008. PMID: 18420585 Free PMC article.

7

Akt attenuation of the serine protease activity of HtrA2/Omi through phosphorylation of serine 212.

Yang L, Sun M, Sun XM, Cheng GZ, Nicosia SV, Cheng JQ. Yang L, et al. Among authors: cheng gz, cheng jq. J Biol Chem. 2016 Oct 21;291(43):22843. doi: 10.1074/jbc.A116.700445. J Biol Chem. 2016. PMID: 27825081 Free PMC article. No abstract available.

8

Regulation of cancer cell survival, migration, and invasion by Twist: AKT2 comes to interplay.

Cheng GZ, Zhang W, Wang LH. Cheng GZ, et al. Cancer Res. 2008 Feb 15;68(4):957-60. doi: 10.1158/0008-5472.CAN-07-5067. Cancer Res. 2008. PMID: 18281467 Review.

9

Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel.

Cheng GZ, Chan J, Wang Q, Zhang W, Sun CD, Wang LH. Cheng GZ, et al. Cancer Res. 2007 Mar 1;67(5):1979-87. doi: 10.1158/0008-5472.CAN-06-1479. Cancer Res. 2007. PMID: 17332325

10

Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1.

Benzeno S, Narla G, Allina J, Cheng GZ, Reeves HL, Banck MS, Odin JA, Diehl JA, Germain D, Friedman SL. Benzeno S, et al. Among authors: cheng gz. Cancer Res. 2004 Jun 1;64(11):3885-91. doi: 10.1158/0008-5472.CAN-03-2818. Cancer Res. 2004. PMID: 15172998

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