Cheng JQ - Search Results

1

Targeting the phosphatidylinositol-3 kinase/Akt pathway for the treatment of cancer.

Kim D, Cheng GZ, Lindsley CW, Yang H, Cheng JQ. Kim D, et al. Among authors: cheng gz, cheng jq. Curr Opin Investig Drugs. 2005 Dec;6(12):1250-8. Curr Opin Investig Drugs. 2005. PMID: 16370391 Review.

2

AKT2, a member of the protein kinase B family, is activated by growth factors, v-Ha-ras, and v-src through phosphatidylinositol 3-kinase in human ovarian epithelial cancer cells.

Liu AX, Testa JR, Hamilton TC, Jove R, Nicosia SV, Cheng JQ. Liu AX, et al. Among authors: cheng jq. Cancer Res. 1998 Jul 15;58(14):2973-7. Cancer Res. 1998. PMID: 9679957

3

Frequent mutations of NF2 and allelic loss from chromosome band 22q12 in malignant mesothelioma: evidence for a two-hit mechanism of NF2 inactivation.

Cheng JQ, Lee WC, Klein MA, Cheng GZ, Jhanwar SC, Testa JR. Cheng JQ, et al. Among authors: cheng gz. Genes Chromosomes Cancer. 1999 Mar;24(3):238-42. Genes Chromosomes Cancer. 1999. PMID: 10451704

4

The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis.

Jiang K, Coppola D, Crespo NC, Nicosia SV, Hamilton AD, Sebti SM, Cheng JQ. Jiang K, et al. Among authors: cheng jq. Mol Cell Biol. 2000 Jan;20(1):139-48. doi: 10.1128/MCB.20.1.139-148.2000. Mol Cell Biol. 2000. PMID: 10594016 Free PMC article.

5

Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer.

Yuan ZQ, Sun M, Feldman RI, Wang G, Ma X, Jiang C, Coppola D, Nicosia SV, Cheng JQ. Yuan ZQ, et al. Among authors: cheng jq. Oncogene. 2000 May 4;19(19):2324-30. doi: 10.1038/sj.onc.1203598. Oncogene. 2000. PMID: 10822383

6

AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells.

Sun M, Wang G, Paciga JE, Feldman RI, Yuan ZQ, Ma XL, Shelley SA, Jove R, Tsichlis PN, Nicosia SV, Cheng JQ. Sun M, et al. Among authors: cheng jq. Am J Pathol. 2001 Aug;159(2):431-7. doi: 10.1016/s0002-9440(10)61714-2. Am J Pathol. 2001. PMID: 11485901 Free PMC article.

7

Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K.

Sun M, Paciga JE, Feldman RI, Yuan Z, Coppola D, Lu YY, Shelley SA, Nicosia SV, Cheng JQ. Sun M, et al. Among authors: cheng jq. Cancer Res. 2001 Aug 15;61(16):5985-91. Cancer Res. 2001. PMID: 11507039

8

Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells.

Yuan ZQ, Feldman RI, Sun M, Olashaw NE, Coppola D, Sussman GE, Shelley SA, Nicosia SV, Cheng JQ. Yuan ZQ, et al. Among authors: cheng jq. J Biol Chem. 2002 Aug 16;277(33):29973-82. doi: 10.1074/jbc.M203636200. Epub 2002 Jun 4. J Biol Chem. 2002. Retraction in: J Biol Chem. 2016 Oct 21;291(43):22849. doi: 10.1074/jbc.A116.203636 PMID: 12048203 Free article. Retracted.

9

Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin.

Dan HC, Sun M, Yang L, Feldman RI, Sui XM, Ou CC, Nellist M, Yeung RS, Halley DJ, Nicosia SV, Pledger WJ, Cheng JQ. Dan HC, et al. Among authors: cheng jq. J Biol Chem. 2002 Sep 20;277(38):35364-70. doi: 10.1074/jbc.M205838200. Epub 2002 Jul 11. J Biol Chem. 2002. Retraction in: J Biol Chem. 2016 Oct 21;291(43):22848. doi: 10.1074/jbc.A116.205838 PMID: 12167664 Free article. Retracted.

10

Telomerase is regulated by c-Jun NH2-terminal kinase in ovarian surface epithelial cells.

Alfonso-De Matte MY, Yang H, Evans MS, Cheng JQ, Kruk PA. Alfonso-De Matte MY, et al. Among authors: cheng jq. Cancer Res. 2002 Aug 15;62(16):4575-8. Cancer Res. 2002. PMID: 12183409

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