Lindsley CW - Search Results

1

Targeting the phosphatidylinositol-3 kinase/Akt pathway for the treatment of cancer.

Kim D, Cheng GZ, Lindsley CW, Yang H, Cheng JQ. Kim D, et al. Among authors: lindsley cw. Curr Opin Investig Drugs. 2005 Dec;6(12):1250-8. Curr Opin Investig Drugs. 2005. PMID: 16370391 Review.

2

The Akt/PKB pathway: molecular target for cancer drug discovery.

Cheng JQ, Lindsley CW, Cheng GZ, Yang H, Nicosia SV. Cheng JQ, et al. Among authors: lindsley cw. Oncogene. 2005 Nov 14;24(50):7482-92. doi: 10.1038/sj.onc.1209088. Oncogene. 2005. PMID: 16288295 Review.

3

Phospholipase D2 mediates survival signaling through direct regulation of Akt in glioblastoma cells.

Bruntz RC, Taylor HE, Lindsley CW, Brown HA. Bruntz RC, et al. Among authors: lindsley cw. J Biol Chem. 2014 Jan 10;289(2):600-16. doi: 10.1074/jbc.M113.532978. Epub 2013 Nov 20. J Biol Chem. 2014. PMID: 24257753 Free PMC article.

4

The PI3K/Akt pathway: recent progress in the development of ATP-competitive and allosteric Akt kinase inhibitors.

Lindsley CW, Barnett SF, Layton ME, Bilodeau MT. Lindsley CW, et al. Curr Cancer Drug Targets. 2008 Feb;8(1):7-18. doi: 10.2174/156800908783497096. Curr Cancer Drug Targets. 2008. PMID: 18288939 Review.

5

Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members.

DeFeo-Jones D, Barnett SF, Fu S, Hancock PJ, Haskell KM, Leander KR, McAvoy E, Robinson RG, Duggan ME, Lindsley CW, Zhao Z, Huber HE, Jones RE. DeFeo-Jones D, et al. Among authors: lindsley cw. Mol Cancer Ther. 2005 Feb;4(2):271-9. Mol Cancer Ther. 2005. PMID: 15713898

6

The Akt/PKB family of protein kinases: a review of small molecule inhibitors and progress towards target validation.

Barnett SF, Bilodeau MT, Lindsley CW. Barnett SF, et al. Among authors: lindsley cw. Curr Top Med Chem. 2005;5(2):109-25. doi: 10.2174/1568026053507714. Curr Top Med Chem. 2005. PMID: 15853641 Review.

7

Recent progress in the development of ATP-competitive and allosteric Akt kinase inhibitors.

Lindsley CW, Barnett SF, Yaroschak M, Bilodeau MT, Layton ME. Lindsley CW, et al. Curr Top Med Chem. 2007;7(14):1349-63. doi: 10.2174/156802607781696864. Curr Top Med Chem. 2007. PMID: 17692025 Review.

8

Insulin reveals Akt signaling as a novel regulator of norepinephrine transporter trafficking and norepinephrine homeostasis.

Robertson SD, Matthies HJ, Owens WA, Sathananthan V, Christianson NS, Kennedy JP, Lindsley CW, Daws LC, Galli A. Robertson SD, et al. Among authors: lindsley cw. J Neurosci. 2010 Aug 25;30(34):11305-16. doi: 10.1523/JNEUROSCI.0126-10.2010. J Neurosci. 2010. PMID: 20739551 Free PMC article.

9

The Akt/PKB family of protein kinases: a review of small molecule inhibitors and progress towards target validation: a 2009 update.

Lindsley CW. Lindsley CW. Curr Top Med Chem. 2010;10(4):458-77. doi: 10.2174/156802610790980602. Curr Top Med Chem. 2010. PMID: 20180757 Review.

10

Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors.

Lindsley CW, Zhao Z, Leister WH, Robinson RG, Barnett SF, Defeo-Jones D, Jones RE, Hartman GD, Huff JR, Huber HE, Duggan ME. Lindsley CW, et al. Bioorg Med Chem Lett. 2005 Feb 1;15(3):761-4. doi: 10.1016/j.bmcl.2004.11.011. Bioorg Med Chem Lett. 2005. PMID: 15664853

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