Gallick GE - Search Results

1

AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines and abrogates downstream angiogenic processes.

Summy JM, Trevino JG, Lesslie DP, Baker CH, Shakespeare WC, Wang Y, Sundaramoorthi R, Metcalf CA 3rd, Keats JA, Sawyer TK, Gallick GE. Summy JM, et al. Among authors: gallick ge. Mol Cancer Ther. 2005 Dec;4(12):1900-11. doi: 10.1158/1535-7163.MCT-05-0171. Mol Cancer Ther. 2005. PMID: 16373705

2

Neuropilin-1 suppresses tumorigenic properties in a human pancreatic adenocarcinoma cell line lacking neuropilin-1 coreceptors.

Gray MJ, Wey JS, Belcheva A, McCarty MF, Trevino JG, Evans DB, Ellis LM, Gallick GE. Gray MJ, et al. Among authors: gallick ge. Cancer Res. 2005 May 1;65(9):3664-70. doi: 10.1158/0008-5472.CAN-04-2229. Cancer Res. 2005. PMID: 15867361

3

Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis.

Trevino JG, Summy JM, Gray MJ, Nilsson MB, Lesslie DP, Baker CH, Gallick GE. Trevino JG, et al. Among authors: gallick ge. Cancer Res. 2005 Aug 15;65(16):7214-22. doi: 10.1158/0008-5472.CAN-04-3858. Cancer Res. 2005. PMID: 16103072

4

c-Src regulates constitutive and EGF-mediated VEGF expression in pancreatic tumor cells through activation of phosphatidyl inositol-3 kinase and p38 MAPK.

Summy JM, Trevino JG, Baker CH, Gallick GE. Summy JM, et al. Among authors: gallick ge. Pancreas. 2005 Oct;31(3):263-74. doi: 10.1097/01.mpa.0000178280.50534.0c. Pancreas. 2005. PMID: 16163059

5

Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model.

Trevino JG, Summy JM, Lesslie DP, Parikh NU, Hong DS, Lee FY, Donato NJ, Abbruzzese JL, Baker CH, Gallick GE. Trevino JG, et al. Among authors: gallick ge. Am J Pathol. 2006 Mar;168(3):962-72. doi: 10.2353/ajpath.2006.050570. Am J Pathol. 2006. PMID: 16507911 Free PMC article.

6

Treatment for advanced tumors: SRC reclaims center stage.

Summy JM, Gallick GE. Summy JM, et al. Among authors: gallick ge. Clin Cancer Res. 2006 Mar 1;12(5):1398-401. doi: 10.1158/1078-0432.CCR-05-2692. Clin Cancer Res. 2006. PMID: 16533761 Review. No abstract available.

7

Inhibition of PDGFR phosphorylation and Src and Akt activity by GN963 leads to therapy of human pancreatic cancer growing orthotopically in nude mice.

Baker CH, Trevino JG, Summy JM, Zhang F, Caron A, Nesbit M, Gallick GE, Fidler IJ. Baker CH, et al. Among authors: gallick ge. Int J Oncol. 2006 Jul;29(1):125-38. Int J Oncol. 2006. PMID: 16773192

8

SRC inhibitors as potential therapeutic agents for human cancers.

Trevino JG, Summy JM, Gallick GE. Trevino JG, et al. Among authors: gallick ge. Mini Rev Med Chem. 2006 Jun;6(6):681-7. doi: 10.2174/138955706777435724. Mini Rev Med Chem. 2006. PMID: 16787379 Review.

9

Src activation of Stat3 is an independent requirement from NF-kappaB activation for constitutive IL-8 expression in human pancreatic adenocarcinoma cells.

Trevino JG, Gray MJ, Nawrocki ST, Summy JM, Lesslie DP, Evans DB, Sawyer TK, Shakespeare WC, Watowich SS, Chiao PJ, McConkey DJ, Gallick GE. Trevino JG, et al. Among authors: gallick ge. Angiogenesis. 2006;9(2):101-10. doi: 10.1007/s10456-006-9038-9. Epub 2006 Jul 27. Angiogenesis. 2006. PMID: 16871430

10

Regulatory role of c-Met in insulin-like growth factor-I receptor-mediated migration and invasion of human pancreatic carcinoma cells.

Bauer TW, Somcio RJ, Fan F, Liu W, Johnson M, Lesslie DP, Evans DB, Gallick GE, Ellis LM. Bauer TW, et al. Among authors: gallick ge. Mol Cancer Ther. 2006 Jul;5(7):1676-82. doi: 10.1158/1535-7163.MCT-05-0175. Mol Cancer Ther. 2006. PMID: 16891453

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