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Unacylated ghrelin is active on the INS-1E rat insulinoma cell line independently of the growth hormone secretagogue receptor type 1a and the corticotropin releasing factor 2 receptor.
Gauna C, Delhanty PJ, van Aken MO, Janssen JA, Themmen AP, Hofland LJ, Culler M, Broglio F, Ghigo E, van der Lely AJ. Gauna C, et al. Mol Cell Endocrinol. 2006 Jun 7;251(1-2):103-11. doi: 10.1016/j.mce.2006.03.040. Epub 2006 Apr 27. Mol Cell Endocrinol. 2006. PMID: 16647196
Intravenous glucose administration in fasting rats has differential effects on acylated and unacylated ghrelin in the portal and systemic circulation: a comparison between portal and peripheral concentrations in anesthetized rats.
Gauna C, Uitterlinden P, Kramer P, Kiewiet RM, Janssen JA, Delhanty PJ, van Aken MO, Ghigo E, Hofland LJ, Themmen AP, van der Lely AJ. Gauna C, et al. Endocrinology. 2007 Nov;148(11):5278-87. doi: 10.1210/en.2007-0225. Epub 2007 Aug 2. Endocrinology. 2007. PMID: 17673520
Unsaturated fatty acids prevent desensitization of the human growth hormone secretagogue receptor by blocking its internalization.
Delhanty PJ, van Kerkwijk A, Huisman M, van de Zande B, Verhoef-Post M, Gauna C, Hofland L, Themmen AP, van der Lely AJ. Delhanty PJ, et al. Among authors: gauna c. Am J Physiol Endocrinol Metab. 2010 Sep;299(3):E497-505. doi: 10.1152/ajpendo.00414.2009. Epub 2010 Jun 29. Am J Physiol Endocrinol Metab. 2010. PMID: 20587751 Free article.
56 results