Gong H - Search Results

1

Animal models of xenobiotic receptors in drug metabolism and diseases.

Gong H, Sinz MW, Feng Y, Chen T, Venkataramanan R, Xie W. Gong H, et al. Methods Enzymol. 2005;400:598-618. doi: 10.1016/S0076-6879(05)00034-0. Methods Enzymol. 2005. PMID: 16399373 Review.

2

Orphan nuclear receptors, PXR and LXR: new ligands and therapeutic potential.

Gong H, Xie W. Gong H, et al. Expert Opin Ther Targets. 2004 Feb;8(1):49-54. doi: 10.1517/14728222.8.1.49. Expert Opin Ther Targets. 2004. PMID: 14996618

3

A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway.

Zhou J, Zhai Y, Mu Y, Gong H, Uppal H, Toma D, Ren S, Evans RM, Xie W. Zhou J, et al. Among authors: gong h. J Biol Chem. 2006 May 26;281(21):15013-20. doi: 10.1074/jbc.M511116200. Epub 2006 Mar 23. J Biol Chem. 2006. PMID: 16556603 Free PMC article.

4

Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor.

Gong H, Guo P, Zhai Y, Zhou J, Uppal H, Jarzynka MJ, Song WC, Cheng SY, Xie W. Gong H, et al. Mol Endocrinol. 2007 Aug;21(8):1781-90. doi: 10.1210/me.2007-0187. Epub 2007 May 29. Mol Endocrinol. 2007. PMID: 17536009

5

Androgen deprivation by activating the liver X receptor.

Lee JH, Gong H, Khadem S, Lu Y, Gao X, Li S, Zhang J, Xie W. Lee JH, et al. Among authors: gong h. Endocrinology. 2008 Aug;149(8):3778-88. doi: 10.1210/en.2007-1605. Epub 2008 May 1. Endocrinology. 2008. PMID: 18450964 Free PMC article.

6

Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice.

Saini SP, Mu Y, Gong H, Toma D, Uppal H, Ren S, Li S, Poloyac SM, Xie W. Saini SP, et al. Among authors: gong h. Hepatology. 2005 Mar;41(3):497-505. doi: 10.1002/hep.20570. Hepatology. 2005. PMID: 15726644

7

Orphan nuclear receptor pregnane X receptor sensitizes oxidative stress responses in transgenic mice and cancerous cells.

Gong H, Singh SV, Singh SP, Mu Y, Lee JH, Saini SP, Toma D, Ren S, Kagan VE, Day BW, Zimniak P, Xie W. Gong H, et al. Mol Endocrinol. 2006 Feb;20(2):279-90. doi: 10.1210/me.2005-0205. Epub 2005 Sep 29. Mol Endocrinol. 2006. PMID: 16195250

8

Activation of LXRs prevents bile acid toxicity and cholestasis in female mice.

Uppal H, Saini SP, Moschetta A, Mu Y, Zhou J, Gong H, Zhai Y, Ren S, Michalopoulos GK, Mangelsdorf DJ, Xie W. Uppal H, et al. Among authors: gong h. Hepatology. 2007 Feb;45(2):422-32. doi: 10.1002/hep.21494. Hepatology. 2007. PMID: 17256725

9

New opportunities for pregnane X receptor (PXR) targeting in drug development. lessons from Enantio- and species-specific PXR ligands identified from a discovery library of amino acid analogues.

Wipf P, Gong H, Janjic JM, Li S, Day BW, Xie W. Wipf P, et al. Among authors: gong h. Mini Rev Med Chem. 2007 Jun;7(6):617-25. doi: 10.2174/138955707780859404. Mini Rev Med Chem. 2007. PMID: 17584160 Review.

10

Identification of oxysterol 7alpha-hydroxylase (Cyp7b1) as a novel retinoid-related orphan receptor alpha (RORalpha) (NR1F1) target gene and a functional cross-talk between RORalpha and liver X receptor (NR1H3).

Wada T, Kang HS, Angers M, Gong H, Bhatia S, Khadem S, Ren S, Ellis E, Strom SC, Jetten AM, Xie W. Wada T, et al. Among authors: gong h. Mol Pharmacol. 2008 Mar;73(3):891-9. doi: 10.1124/mol.107.040741. Epub 2007 Nov 30. Mol Pharmacol. 2008. PMID: 18055760

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