Xie W - Search Results

1

Animal models of xenobiotic receptors in drug metabolism and diseases.

Gong H, Sinz MW, Feng Y, Chen T, Venkataramanan R, Xie W. Gong H, et al. Among authors: xie w. Methods Enzymol. 2005;400:598-618. doi: 10.1016/S0076-6879(05)00034-0. Methods Enzymol. 2005. PMID: 16399373 Review.

2

A nuclear receptor-mediated xenobiotic response and its implication in drug metabolism and host protection.

Sonoda J, Rosenfeld JM, Xu L, Evans RM, Xie W. Sonoda J, et al. Among authors: xie w. Curr Drug Metab. 2003 Feb;4(1):59-72. doi: 10.2174/1389200033336739. Curr Drug Metab. 2003. PMID: 12570746 Review.

3

Control of steroid, heme, and carcinogen metabolism by nuclear pregnane X receptor and constitutive androstane receptor.

Xie W, Yeuh MF, Radominska-Pandya A, Saini SP, Negishi Y, Bottroff BS, Cabrera GY, Tukey RH, Evans RM. Xie W, et al. Proc Natl Acad Sci U S A. 2003 Apr 1;100(7):4150-5. doi: 10.1073/pnas.0438010100. Epub 2003 Mar 18. Proc Natl Acad Sci U S A. 2003. PMID: 12644700 Free PMC article.

4

A novel constitutive androstane receptor-mediated and CYP3A-independent pathway of bile acid detoxification.

Saini SP, Sonoda J, Xu L, Toma D, Uppal H, Mu Y, Ren S, Moore DD, Evans RM, Xie W. Saini SP, et al. Among authors: xie w. Mol Pharmacol. 2004 Feb;65(2):292-300. doi: 10.1124/mol.65.2.292. Mol Pharmacol. 2004. PMID: 14742670

5

Orphan nuclear receptors, PXR and LXR: new ligands and therapeutic potential.

Gong H, Xie W. Gong H, et al. Among authors: xie w. Expert Opin Ther Targets. 2004 Feb;8(1):49-54. doi: 10.1517/14728222.8.1.49. Expert Opin Ther Targets. 2004. PMID: 14996618

6

Coactivators in assay design for nuclear hormone receptor drug discovery.

Chen T, Xie W, Agler M, Banks M. Chen T, et al. Among authors: xie w. Assay Drug Dev Technol. 2003 Dec;1(6):835-42. doi: 10.1089/154065803772613462. Assay Drug Dev Technol. 2003. PMID: 15090229 Review.

7

Orphan nuclear receptor-mediated xenobiotic regulation in drug metabolism.

Xie W, Uppal H, Saini SP, Mu Y, Little JM, Radominska-Pandya A, Zemaitis MA. Xie W, et al. Drug Discov Today. 2004 May 15;9(10):442-9. doi: 10.1016/S1359-6446(04)03061-2. Drug Discov Today. 2004. PMID: 15109949 Review. No abstract available.

8

Combined loss of orphan receptors PXR and CAR heightens sensitivity to toxic bile acids in mice.

Uppal H, Toma D, Saini SP, Ren S, Jones TJ, Xie W. Uppal H, et al. Among authors: xie w. Hepatology. 2005 Jan;41(1):168-76. doi: 10.1002/hep.20512. Hepatology. 2005. PMID: 15619241

9

Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice.

Saini SP, Mu Y, Gong H, Toma D, Uppal H, Ren S, Li S, Poloyac SM, Xie W. Saini SP, et al. Among authors: xie w. Hepatology. 2005 Mar;41(3):497-505. doi: 10.1002/hep.20570. Hepatology. 2005. PMID: 15726644

10

A pregnane X receptor agonist with unique species-dependent stereoselectivity and its implications in drug development.

Mu Y, Stephenson CR, Kendall C, Saini SP, Toma D, Ren S, Cai H, Strom SC, Day BW, Wipf P, Xie W. Mu Y, et al. Among authors: xie w. Mol Pharmacol. 2005 Aug;68(2):403-13. doi: 10.1124/mol.105.013292. Epub 2005 May 4. Mol Pharmacol. 2005. PMID: 15872116

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