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Page 1
Small molecule protein assembly modulators with pan-cancer therapeutic efficacy.
Lingappa AF, Akintunde O, Samueli E, Ewald C, Michon M, Ziari N, Lu M, Yu SF, Froehlich M, Le PU, Fernandez Y, Mallesh S, Lin J, Kitaygorodskyy A, Solas D, Reed JC, Lingappa JR, Müller-Schiffmann A, Korth C, Prasad D, Nalca A, Aston E, Fabbri B, Anand SK, Campi TW, Petrouski E, Dey D, Andrews DW, Rubenstein JL, Lingappa VR. Lingappa AF, et al. Among authors: yu sf. Open Biol. 2024 Dec;14(12):240210. doi: 10.1098/rsob.240210. Epub 2024 Dec 18. Open Biol. 2024. PMID: 39689856 Free PMC article.
NKG2D-bispecific enhances NK and CD8+ T cell antitumor immunity.
Herault A, Mak J, de la Cruz-Chuh J, Dillon MA, Ellerman D, Go M, Cosino E, Clark R, Carson E, Yeung S, Pichery M, Gador M, Chiang EY, Wu J, Liang Y, Modrusan Z, Gampa G, Sudhamsu J, Kemball CC, Cheung V, Nguyen TTT, Seshasayee D, Piskol R, Totpal K, Yu SF, Lee G, Kozak KR, Spiess C, Walsh KB. Herault A, et al. Among authors: yu sf. Cancer Immunol Immunother. 2024 Aug 8;73(10):209. doi: 10.1007/s00262-024-03795-2. Cancer Immunol Immunother. 2024. PMID: 39112670 Free PMC article.
On Demand Bioorthogonal Switching of an Antibody-Conjugated SPECT Probe to a Cytotoxic Payload: from Imaging to Therapy.
Adhikari P, Li G, Go M, Mandikian D, Rafidi H, Ng C, Anifa S, Johnson K, Bao L, Hernandez Barry H, Rowntree R, Agard N, Wu C, Chou KJ, Zhang D, Kozak KR, Pillow TH, Lewis GD, Yu SF, Boswell CA, Sadowsky JD. Adhikari P, et al. Among authors: yu sf. J Am Chem Soc. 2024 Jul 17;146(28):19088-19100. doi: 10.1021/jacs.4c03529. Epub 2024 Jul 1. J Am Chem Soc. 2024. PMID: 38946086
A pan-respiratory antiviral chemotype targeting a transient host multi-protein complex.
Michon M, Müller-Schiffmann A, Lingappa AF, Yu SF, Du L, Deiter F, Broce S, Mallesh S, Crabtree J, Lingappa UF, Macieik A, Müller L, Ostermann PN, Andrée M, Adams O, Schaal H, Hogan RJ, Tripp RA, Appaiah U, Anand SK, Campi TW, Ford MJ, Reed JC, Lin J, Akintunde O, Copeland K, Nichols C, Petrouski E, Moreira AR, Jiang IT, DeYarman N, Brown I, Lau S, Segal I, Goldsmith D, Hong S, Asundi V, Briggs EM, Phyo NS, Froehlich M, Onisko B, Matlack K, Dey D, Lingappa JR, Prasad DM, Kitaygorodskyy A, Solas D, Boushey H, Greenland J, Pillai S, Lo MK, Montgomery JM, Spiropoulou CF, Korth C, Selvarajah S, Paulvannan K, Lingappa VR. Michon M, et al. Among authors: yu sf. Open Biol. 2024 Jun;14(6):230363. doi: 10.1098/rsob.230363. Epub 2024 Jun 19. Open Biol. 2024. PMID: 38889796 Free PMC article.
505 results