Subramaniam S - Search Results

1

Purification of MINUS: A negative regulator of microtubule nucleation in a variety of organisms.

Shahani N, Subramaniam S, Brandt R. Shahani N, et al. Among authors: subramaniam s. Int J Biol Macromol. 2006 Aug 15;39(1-3):15-22. doi: 10.1016/j.ijbiomac.2005.12.014. Epub 2006 Jan 18. Int J Biol Macromol. 2006. PMID: 16420961

2

Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway.

Subramaniam S, Shahani N, Strelau J, Laliberté C, Brandt R, Kaplan D, Unsicker K. Subramaniam S, et al. J Neurosci. 2005 Mar 16;25(11):2838-52. doi: 10.1523/JNEUROSCI.5060-04.2005. J Neurosci. 2005. PMID: 15772344 Free PMC article.

3

Tau aggregation and progressive neuronal degeneration in the absence of changes in spine density and morphology after targeted expression of Alzheimer's disease-relevant tau constructs in organotypic hippocampal slices.

Shahani N, Subramaniam S, Wolf T, Tackenberg C, Brandt R. Shahani N, et al. Among authors: subramaniam s. J Neurosci. 2006 May 31;26(22):6103-14. doi: 10.1523/JNEUROSCI.4245-05.2006. J Neurosci. 2006. PMID: 16738255 Free PMC article.

4

Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.

Subramaniam S, Napolitano F, Mealer RG, Kim S, Errico F, Barrow R, Shahani N, Tyagi R, Snyder SH, Usiello A. Subramaniam S, et al. Nat Neurosci. 2011 Dec 18;15(2):191-3. doi: 10.1038/nn.2994. Nat Neurosci. 2011. PMID: 22179112 Free PMC article.

5

Rhes, a striatal-selective protein implicated in Huntington disease, binds beclin-1 and activates autophagy.

Mealer RG, Murray AJ, Shahani N, Subramaniam S, Snyder SH. Mealer RG, et al. Among authors: subramaniam s. J Biol Chem. 2014 Feb 7;289(6):3547-54. doi: 10.1074/jbc.M113.536912. Epub 2013 Dec 9. J Biol Chem. 2014. PMID: 24324270 Free PMC article.

6

Rheb GTPase regulates β-secretase levels and amyloid β generation.

Shahani N, Pryor W, Swarnkar S, Kholodilov N, Thinakaran G, Burke RE, Subramaniam S. Shahani N, et al. Among authors: subramaniam s. J Biol Chem. 2014 Feb 28;289(9):5799-808. doi: 10.1074/jbc.M113.532713. Epub 2013 Dec 24. J Biol Chem. 2014. PMID: 24368770 Free PMC article.

7

Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease.

Pryor WM, Biagioli M, Shahani N, Swarnkar S, Huang WC, Page DT, MacDonald ME, Subramaniam S. Pryor WM, et al. Among authors: subramaniam s. Sci Signal. 2014 Oct 28;7(349):ra103. doi: 10.1126/scisignal.2005633. Sci Signal. 2014. PMID: 25351248

8

Rheb Inhibits Protein Synthesis by Activating the PERK-eIF2α Signaling Cascade.

Tyagi R, Shahani N, Gorgen L, Ferretti M, Pryor W, Chen PY, Swarnkar S, Worley PF, Karbstein K, Snyder SH, Subramaniam S. Tyagi R, et al. Among authors: subramaniam s. Cell Rep. 2015 Feb 10;10(5):684-693. doi: 10.1016/j.celrep.2015.01.014. Epub 2015 Feb 7. Cell Rep. 2015. PMID: 25660019 Free PMC article.

9

Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease.

Swarnkar S, Chen Y, Pryor WM, Shahani N, Page DT, Subramaniam S. Swarnkar S, et al. Among authors: subramaniam s. Neurobiol Dis. 2015 Oct;82:66-77. doi: 10.1016/j.nbd.2015.05.011. Epub 2015 Jun 3. Neurobiol Dis. 2015. PMID: 26048156

10

RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum.

Shahani N, Swarnkar S, Giovinazzo V, Morgenweck J, Bohn LM, Scharager-Tapia C, Pascal B, Martinez-Acedo P, Khare K, Subramaniam S. Shahani N, et al. Among authors: subramaniam s. Sci Signal. 2016 Nov 15;9(454):ra111. doi: 10.1126/scisignal.aaf6670. Sci Signal. 2016. PMID: 27902448 Free PMC article.

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