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Efficient synthesis of NK(1) receptor antagonist aprepitant using a crystallization-induced diastereoselective transformation.
Brands KM, Payack JF, Rosen JD, Nelson TD, Candelario A, Huffman MA, Zhao MM, Li J, Craig B, Song ZJ, Tschaen DM, Hansen K, Devine PN, Pye PJ, Rossen K, Dormer PG, Reamer RA, Welch CJ, Mathre DJ, Tsou NN, McNamara JM, Reider PJ. Brands KM, et al. Among authors: li j. J Am Chem Soc. 2003 Feb 26;125(8):2129-35. doi: 10.1021/ja027458g. J Am Chem Soc. 2003. PMID: 12590540
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