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Profiling genetic variation along the androgen biosynthesis and metabolism pathways implicates several single nucleotide polymorphisms and their combinations as prostate cancer risk factors.
Mononen N, Seppälä EH, Duggal P, Autio V, Ikonen T, Ellonen P, Saharinen J, Saarela J, Vihinen M, Tammela TL, Kallioniemi O, Bailey-Wilson JE, Schleutker J. Mononen N, et al. Among authors: ikonen t. Cancer Res. 2006 Jan 15;66(2):743-7. doi: 10.1158/0008-5472.CAN-05-1723. Cancer Res. 2006. PMID: 16424004
Germline alterations of the RNASEL gene, a candidate HPC1 gene at 1q25, in patients and families with prostate cancer.
Rökman A, Ikonen T, Seppälä EH, Nupponen N, Autio V, Mononen N, Bailey-Wilson J, Trent J, Carpten J, Matikainen MP, Koivisto PA, Tammela TL, Kallioniemi OP, Schleutker J. Rökman A, et al. Among authors: ikonen t. Am J Hum Genet. 2002 May;70(5):1299-304. doi: 10.1086/340450. Epub 2002 Apr 8. Am J Hum Genet. 2002. PMID: 11941539 Free PMC article.
Androgen receptor CAG polymorphism and prostate cancer risk.
Mononen N, Ikonen T, Autio V, Rökman A, Matikainen MP, Tammela TL, Kallioniemi OP, Koivisto PA, Schleutker J. Mononen N, et al. Among authors: ikonen t. Hum Genet. 2002 Aug;111(2):166-71. doi: 10.1007/s00439-002-0776-5. Epub 2002 Jul 3. Hum Genet. 2002. PMID: 12189490
CHEK2 variants associate with hereditary prostate cancer.
Seppälä EH, Ikonen T, Mononen N, Autio V, Rökman A, Matikainen MP, Tammela TL, Schleutker J. Seppälä EH, et al. Among authors: ikonen t. Br J Cancer. 2003 Nov 17;89(10):1966-70. doi: 10.1038/sj.bjc.6601425. Br J Cancer. 2003. PMID: 14612911 Free PMC article.
Germ-line alterations in MSR1 gene and prostate cancer risk.
Seppälä EH, Ikonen T, Autio V, Rökman A, Mononen N, Matikainen MP, Tammela TL, Schleutker J. Seppälä EH, et al. Among authors: ikonen t. Clin Cancer Res. 2003 Nov 1;9(14):5252-6. Clin Cancer Res. 2003. PMID: 14614006
162 results