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H2AX prevents DNA breaks from progressing to chromosome breaks and translocations.
Franco S, Gostissa M, Zha S, Lombard DB, Murphy MM, Zarrin AA, Yan C, Tepsuporn S, Morales JC, Adams MM, Lou Z, Bassing CH, Manis JP, Chen J, Carpenter PB, Alt FW. Franco S, et al. Among authors: morales jc. Mol Cell. 2006 Jan 20;21(2):201-14. doi: 10.1016/j.molcel.2006.01.005. Mol Cell. 2006. PMID: 16427010 Free article.
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1.
Fernandez-Capetillo O, Chen HT, Celeste A, Ward I, Romanienko PJ, Morales JC, Naka K, Xia Z, Camerini-Otero RD, Motoyama N, Carpenter PB, Bonner WM, Chen J, Nussenzweig A. Fernandez-Capetillo O, et al. Among authors: morales jc. Nat Cell Biol. 2002 Dec;4(12):993-7. doi: 10.1038/ncb884. Nat Cell Biol. 2002. PMID: 12447390
53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis.
Morales JC, Franco S, Murphy MM, Bassing CH, Mills KD, Adams MM, Walsh NC, Manis JP, Rassidakis GZ, Alt FW, Carpenter PB. Morales JC, et al. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3310-5. doi: 10.1073/pnas.0511259103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492765 Free PMC article.
53BP1 oligomerization is independent of its methylation by PRMT1.
Adams MM, Wang B, Xia Z, Morales JC, Lu X, Donehower LA, Bochar DA, Elledge SJ, Carpenter PB. Adams MM, et al. Among authors: morales jc. Cell Cycle. 2005 Dec;4(12):1854-61. doi: 10.4161/cc.4.12.2282. Epub 2005 Dec 28. Cell Cycle. 2005. PMID: 16294047
Breaking in a new function for casein kinase 2.
Morales JC, Carpenter PB. Morales JC, et al. Sci Aging Knowledge Environ. 2004 Jun 2;2004(22):pe24. doi: 10.1126/sageke.2004.22.pe24. Sci Aging Knowledge Environ. 2004. PMID: 15175499 Review.
196 results