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The First Anti-Snakebite and Hepatoprotective Characterization of a Trypsin Kunitz-like Inhibitor (EcTI) from the Plant Enterolobium contortisiliquum; A Case of Two Soul Mates Meeting.
Costa CRC, Belchor MN, Roggero A, Moraes LL, Samelo R, Annunciato I, Bonturi CR, Oliva MLV, Sousa SF, de Oliveira MA, Toyama MH. Costa CRC, et al. Among authors: toyama mh. Pharmaceuticals (Basel). 2023 Apr 21;16(4):632. doi: 10.3390/ph16040632. Pharmaceuticals (Basel). 2023. PMID: 37111388 Free PMC article.
In Silico Evaluation of Quercetin Methylated Derivatives on the Interaction with Secretory Phospholipases A2 from Crotalus durissus terrificus and Bothrops jararacussu.
Belchor MN, Costa CRDC, Roggero A, Moraes LLF, Samelo R, Annunciato I, de Oliveira MA, Sousa SF, Toyama MH. Belchor MN, et al. Among authors: toyama mh. Pharmaceuticals (Basel). 2023 Apr 15;16(4):597. doi: 10.3390/ph16040597. Pharmaceuticals (Basel). 2023. PMID: 37111354 Free PMC article.
Adenanthin Is an Efficient Inhibitor of Peroxiredoxins from Pathogens, Inhibits Bacterial Growth, and Potentiates Antibiotic Activities.
Dos Santos MC, Tairum CA, Cabrera VIM, Guimarães Cauz AC, Ribeiro LF, Toledo Junior JC, Toyama MH, Lago JHG, Brocchi M, Netto LES, de Oliveira MA. Dos Santos MC, et al. Among authors: toyama mh. Chem Res Toxicol. 2023 Apr 17;36(4):570-582. doi: 10.1021/acs.chemrestox.2c00049. Epub 2022 May 10. Chem Res Toxicol. 2023. PMID: 35537067
Bothrops pauloensis snake venom-derived Asp-49 and Lys-49 phospholipases A2 mediates acute kidney injury by oxidative stress and release of inflammatory cytokines.
Marinho AD, Silveira JAM, Chaves Filho AJM, Jorge ARC, Nogueira Júnior FA, Pereira VBM, de Aquino PEA, Pereira CAS, Evangelista JSAM, Macedo DS, Lima Júnior RCP, Toyama MH, Jorge RJB, Pereira GJS, Monteiro HSA. Marinho AD, et al. Among authors: toyama mh. Toxicon. 2021 Jan 30;190:31-38. doi: 10.1016/j.toxicon.2020.12.004. Epub 2020 Dec 9. Toxicon. 2021. PMID: 33307108
Influence of lysosomal protease sensitivity in the immunogenicity of the antitumor biopharmaceutical asparaginase.
Rodrigues MAD, Pimenta MV, Costa IM, Zenatti PP, Migita NA, Yunes JA, Rangel-Yagui CO, de Sá MM, Pessoa A, Costa-Silva TA, Toyama MH, Breyer CA, de Oliveira MA, Santiago VF, Palmisano G, Barbosa CMV, Hebeda CB, Farsky SHP, Monteiro G. Rodrigues MAD, et al. Among authors: toyama mh. Biochem Pharmacol. 2020 Dec;182:114230. doi: 10.1016/j.bcp.2020.114230. Epub 2020 Sep 23. Biochem Pharmacol. 2020. PMID: 32979352 Free article.
The Human Pathogen Paracoccidioides brasiliensis Has a Unique 1-Cys Peroxiredoxin That Localizes Both Intracellularly and at the Cell Surface.
Longo LVG, Breyer CA, Novaes GM, Gegembauer G, Leitão NP Jr, Octaviano CE, Toyama MH, de Oliveira MA, Puccia R. Longo LVG, et al. Among authors: toyama mh. Front Cell Infect Microbiol. 2020 Aug 4;10:394. doi: 10.3389/fcimb.2020.00394. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32850492 Free PMC article.
148 results