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Page 1
Discovery of FabH/FabF inhibitors from natural products.
Young K, Jayasuriya H, Ondeyka JG, Herath K, Zhang C, Kodali S, Galgoci A, Painter R, Brown-Driver V, Yamamoto R, Silver LL, Zheng Y, Ventura JI, Sigmund J, Ha S, Basilio A, Vicente F, Tormo JR, Pelaez F, Youngman P, Cully D, Barrett JF, Schmatz D, Singh SB, Wang J. Young K, et al. Among authors: singh sb. Antimicrob Agents Chemother. 2006 Feb;50(2):519-26. doi: 10.1128/AAC.50.2.519-526.2006. Antimicrob Agents Chemother. 2006. PMID: 16436705 Free PMC article.
A novel antiviral agent which inhibits the endonuclease of influenza viruses.
Tomassini JE, Davies ME, Hastings JC, Lingham R, Mojena M, Raghoobar SL, Singh SB, Tkacz JS, Goetz MA. Tomassini JE, et al. Among authors: singh sb. Antimicrob Agents Chemother. 1996 May;40(5):1189-93. doi: 10.1128/AAC.40.5.1189. Antimicrob Agents Chemother. 1996. PMID: 8723464 Free PMC article.
Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase.
Darkin-Rattray SJ, Gurnett AM, Myers RW, Dulski PM, Crumley TM, Allocco JJ, Cannova C, Meinke PT, Colletti SL, Bednarek MA, Singh SB, Goetz MA, Dombrowski AW, Polishook JD, Schmatz DM. Darkin-Rattray SJ, et al. Among authors: singh sb. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13143-7. doi: 10.1073/pnas.93.23.13143. Proc Natl Acad Sci U S A. 1996. PMID: 8917558 Free PMC article.
Oreganic acid, a potent inhibitor of ras farnesyl-protein transferase.
Silverman KC, Jayasuriya H, Cascales C, Vilella D, Bills GF, Jenkins RG, Singh SB, Lingham RB. Silverman KC, et al. Among authors: singh sb. Biochem Biophys Res Commun. 1997 Mar 17;232(2):478-81. doi: 10.1006/bbrc.1997.6314. Biochem Biophys Res Commun. 1997. PMID: 9125205
Coprophilin: an anticoccidial agent produced by a dung inhabiting fungus.
Ondeyka JG, Giacobbe RA, Bills GF, Cuadrillero C, Schmatz D, Goetz MA, Zink DL, Singh SB. Ondeyka JG, et al. Among authors: singh sb. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3439-42. doi: 10.1016/s0960-894x(98)00629-5. Bioorg Med Chem Lett. 1998. PMID: 9934448
Inhibitors of farnesylation of Ras from a microbial natural products screening program.
Vilella D, Sánchez M, Platas G, Salazar O, Genilloud O, Royo I, Cascales C, Martín I, Díez T, Silverman KC, Lingham RB, Singh SB, Jayasuriya H, Peláez F. Vilella D, et al. Among authors: singh sb. J Ind Microbiol Biotechnol. 2000 Dec;25(6):315-327. doi: 10.1038/sj.jim.7000085. J Ind Microbiol Biotechnol. 2000. PMID: 11320419
The complestatins as HIV-1 integrase inhibitors. Efficient isolation, structure elucidation, and inhibitory activities of isocomplestatin, chloropeptin I, new complestatins, A and B, and acid-hydrolysis products of chloropeptin I.
Singh SB, Jayasuriya H, Salituro GM, Zink DL, Shafiee A, Heimbuch B, Silverman KC, Lingham RB, Genilloud O, Teran A, Vilella D, Felock P, Hazuda D. Singh SB, et al. J Nat Prod. 2001 Jul;64(7):874-82. doi: 10.1021/np000632z. J Nat Prod. 2001. PMID: 11473415
824 results