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Page 1
Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations.
Radomska HS, Bassères DS, Zheng R, Zhang P, Dayaram T, Yamamoto Y, Sternberg DW, Lokker N, Giese NA, Bohlander SK, Schnittger S, Delmotte MH, Davis RJ, Small D, Hiddemann W, Gilliland DG, Tenen DG. Radomska HS, et al. Among authors: gilliland dg. J Exp Med. 2006 Feb 20;203(2):371-81. doi: 10.1084/jem.20052242. Epub 2006 Jan 30. J Exp Med. 2006. PMID: 16446383 Free PMC article.
CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML).
Kelly LM, Yu JC, Boulton CL, Apatira M, Li J, Sullivan CM, Williams I, Amaral SM, Curley DP, Duclos N, Neuberg D, Scarborough RM, Pandey A, Hollenbach S, Abe K, Lokker NA, Gilliland DG, Giese NA. Kelly LM, et al. Among authors: gilliland dg. Cancer Cell. 2002 Jun;1(5):421-32. doi: 10.1016/s1535-6108(02)00070-3. Cancer Cell. 2002. PMID: 12124172 Free article.
Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.
Wagner K, Zhang P, Rosenbauer F, Drescher B, Kobayashi S, Radomska HS, Kutok JL, Gilliland DG, Krauter J, Tenen DG. Wagner K, et al. Among authors: gilliland dg. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6338-43. doi: 10.1073/pnas.0508143103. Epub 2006 Apr 10. Proc Natl Acad Sci U S A. 2006. PMID: 16606850 Free PMC article.
The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3.
Spiekermann K, Dirschinger RJ, Schwab R, Bagrintseva K, Faber F, Buske C, Schnittger S, Kelly LM, Gilliland DG, Hiddemann W. Spiekermann K, et al. Among authors: gilliland dg. Blood. 2003 Feb 15;101(4):1494-504. doi: 10.1182/blood-2002-04-1045. Epub 2002 Oct 24. Blood. 2003. PMID: 12406902 Free article.
PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis.
Huang G, Zhang P, Hirai H, Elf S, Yan X, Chen Z, Koschmieder S, Okuno Y, Dayaram T, Growney JD, Shivdasani RA, Gilliland DG, Speck NA, Nimer SD, Tenen DG. Huang G, et al. Among authors: gilliland dg. Nat Genet. 2008 Jan;40(1):51-60. doi: 10.1038/ng.2007.7. Epub 2007 Nov 11. Nat Genet. 2008. PMID: 17994017
275 results