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Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations.
Radomska HS, Bassères DS, Zheng R, Zhang P, Dayaram T, Yamamoto Y, Sternberg DW, Lokker N, Giese NA, Bohlander SK, Schnittger S, Delmotte MH, Davis RJ, Small D, Hiddemann W, Gilliland DG, Tenen DG. Radomska HS, et al. Among authors: hiddemann w. J Exp Med. 2006 Feb 20;203(2):371-81. doi: 10.1084/jem.20052242. Epub 2006 Jan 30. J Exp Med. 2006. PMID: 16446383 Free PMC article.
Heterozygous PU.1 mutations are associated with acute myeloid leukemia.
Mueller BU, Pabst T, Osato M, Asou N, Johansen LM, Minden MD, Behre G, Hiddemann W, Ito Y, Tenen DG. Mueller BU, et al. Among authors: hiddemann w. Blood. 2002 Aug 1;100(3):998-1007. doi: 10.1182/blood.v100.3.998. Blood. 2002. PMID: 12130514 Free article.
The protein tyrosine kinase inhibitor SU5614 inhibits FLT3 and induces growth arrest and apoptosis in AML-derived cell lines expressing a constitutively activated FLT3.
Spiekermann K, Dirschinger RJ, Schwab R, Bagrintseva K, Faber F, Buske C, Schnittger S, Kelly LM, Gilliland DG, Hiddemann W. Spiekermann K, et al. Among authors: hiddemann w. Blood. 2003 Feb 15;101(4):1494-504. doi: 10.1182/blood-2002-04-1045. Epub 2002 Oct 24. Blood. 2003. PMID: 12406902 Free article.
The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice.
Schessl C, Rawat VP, Cusan M, Deshpande A, Kohl TM, Rosten PM, Spiekermann K, Humphries RK, Schnittger S, Kern W, Hiddemann W, Quintanilla-Martinez L, Bohlander SK, Feuring-Buske M, Buske C. Schessl C, et al. Among authors: hiddemann w. J Clin Invest. 2005 Aug;115(8):2159-68. doi: 10.1172/JCI24225. Epub 2005 Jul 14. J Clin Invest. 2005. PMID: 16025155 Free PMC article.
A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis.
Petropoulos K, Arseni N, Schessl C, Stadler CR, Rawat VP, Deshpande AJ, Heilmeier B, Hiddemann W, Quintanilla-Martinez L, Bohlander SK, Feuring-Buske M, Buske C. Petropoulos K, et al. Among authors: hiddemann w. J Exp Med. 2008 Mar 17;205(3):515-22. doi: 10.1084/jem.20071875. Epub 2008 Mar 3. J Exp Med. 2008. PMID: 18316418 Free PMC article.
916 results