Jarkas N - Search Results

1

Evaluation of carbon-11-labeled 2beta-carbomethoxy-3beta-[4'-((Z)-2-iodoethenyl)phenyl]nortropane as a potential radioligand for imaging the serotonin transporter by PET.

Plisson C, Jarkas N, McConathy J, Voll RJ, Votaw J, Williams L, Howell LL, Kilts CD, Goodman MM. Plisson C, et al. Among authors: jarkas n. J Med Chem. 2006 Feb 9;49(3):942-6. doi: 10.1021/jm050799v. J Med Chem. 2006. PMID: 16451060

2

Synthesis and characterization of EADAM: a selective radioligand for mapping the brain serotonin transporters by positron emission tomography.

Jarkas N, McConathy J, Votaw JR, Voll RJ, Malveaux E, Camp VM, Williams L, Goodman RR, Kilts CD, Goodman MM. Jarkas N, et al. Nucl Med Biol. 2005 Jan;32(1):75-86. doi: 10.1016/j.nucmedbio.2004.07.001. Nucl Med Biol. 2005. PMID: 15691664

3

Carbon-11 HOMADAM: a novel PET radiotracer for imaging serotonin transporters.

Jarkas N, Votaw JR, Voll RJ, Williams L, Camp VM, Owens MJ, Purselle DC, Bremner JD, Kilts CD, Nemeroff CB, Goodman MM. Jarkas N, et al. Nucl Med Biol. 2005 Apr;32(3):211-24. doi: 10.1016/j.nucmedbio.2004.11.007. Nucl Med Biol. 2005. PMID: 15820756

4

Synthesis, in vitro characterization, and radiolabeling of N,N-dimethyl-2-(2'-amino-4'-substituted-phenylthio)benzylamines: potential candidates as selective serotonin transporter radioligands.

Jarkas N, McConathy J, Voll RJ, Goodman MM. Jarkas N, et al. J Med Chem. 2005 Jun 30;48(13):4254-65. doi: 10.1021/jm050079o. J Med Chem. 2005. PMID: 15974579

5

Synthesis, radiosynthesis, and biological evaluation of carbon-11 and fluorine-18 (N-fluoroalkyl) labeled 2beta-carbomethoxy-3beta-(4'-(3-furyl)phenyl)tropanes and -nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography.

Stehouwer JS, Plisson C, Jarkas N, Zeng F, Voll RJ, Williams L, Martarello L, Votaw JR, Tamagnan G, Goodman MM. Stehouwer JS, et al. Among authors: jarkas n. J Med Chem. 2005 Nov 3;48(22):7080-3. doi: 10.1021/jm0504095. J Med Chem. 2005. PMID: 16250668

6

Synthesis and monoamine transporter affinity of front bridged tricyclic 3beta-(4'-halo or 4'-methyl)phenyltropanes bearing methylene or carbomethoxymethylene on the bridge to the 2beta-position.

Zeng F, Jarkas N, Owens MJ, Kilts CD, Nemeroff CB, Goodman MM. Zeng F, et al. Among authors: jarkas n. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4661-3. doi: 10.1016/j.bmcl.2006.05.098. Epub 2006 Jun 19. Bioorg Med Chem Lett. 2006. PMID: 16784855

7

Synthesis, radiosynthesis, and biological evaluation of carbon-11 labeled 2beta-carbomethoxy-3beta-(3'-((Z)-2-haloethenyl)phenyl)nortropanes: candidate radioligands for in vivo imaging of the serotonin transporter with positron emission tomography.

Stehouwer JS, Jarkas N, Zeng F, Voll RJ, Williams L, Owens MJ, Votaw JR, Goodman MM. Stehouwer JS, et al. Among authors: jarkas n. J Med Chem. 2006 Nov 16;49(23):6760-7. doi: 10.1021/jm060641q. J Med Chem. 2006. PMID: 17154506

8

Synthesis and biological evaluation of 2beta,3alpha-(substituted phenyl)nortropanes as potential norepinephrine transporter imaging agents.

Zeng F, Stehouwer JS, Jarkas N, Voll RJ, Williams L, Camp VM, Votaw JR, Owens MJ, Kilts CD, Nemeroff CB, Goodman MM. Zeng F, et al. Among authors: jarkas n. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3044-7. doi: 10.1016/j.bmcl.2007.03.056. Epub 2007 Mar 23. Bioorg Med Chem Lett. 2007. PMID: 17446069

9

Synthesis, in vitro characterization, and radiolabeling of reboxetine analogs as potential PET radioligands for imaging the norepinephrine transporter.

Zeng F, Jarkas N, Stehouwer JS, Voll RJ, Owens MJ, Kilts CD, Nemeroff CB, Goodman MM. Zeng F, et al. Among authors: jarkas n. Bioorg Med Chem. 2008 Jan 15;16(2):783-93. doi: 10.1016/j.bmc.2007.10.025. Epub 2007 Oct 13. Bioorg Med Chem. 2008. PMID: 17983754

10

Synthesis and in vivo evaluation of halogenated N,N-dimethyl-2-(2'-amino-4'-hydroxymethylphenylthio)benzylamine derivatives as PET serotonin transporter ligands.

Jarkas N, Voll RJ, Williams L, Votaw JR, Owens M, Goodman MM. Jarkas N, et al. J Med Chem. 2008 Jan 24;51(2):271-81. doi: 10.1021/jm0707929. Epub 2007 Dec 18. J Med Chem. 2008. PMID: 18085744

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