Ji X - Search Results

1

PABA/NO as an anticancer lead: analogue synthesis, structure revision, solution chemistry, reactivity toward glutathione, and in vitro activity.

Saavedra JE, Srinivasan A, Buzard GS, Davies KM, Waterhouse DJ, Inami K, Wilde TC, Citro ML, Cuellar M, Deschamps JR, Parrish D, Shami PJ, Findlay VJ, Townsend DM, Tew KD, Singh S, Jia L, Ji X, Keefer LK. Saavedra JE, et al. Among authors: ji x. J Med Chem. 2006 Feb 9;49(3):1157-64. doi: 10.1021/jm050700k. J Med Chem. 2006. PMID: 16451080 Free PMC article.

2

Crystal structure of shikimate kinase from Mycobacterium tuberculosis reveals the dynamic role of the LID domain in catalysis.

Gu Y, Reshetnikova L, Li Y, Wu Y, Yan H, Singh S, Ji X. Gu Y, et al. Among authors: ji x. J Mol Biol. 2002 Jun 7;319(3):779-89. doi: 10.1016/S0022-2836(02)00339-X. J Mol Biol. 2002. PMID: 12054870

3

Residues 207, 216, and 221 and the catalytic activity of mGSTA1-1 and mGSTA2-2 toward benzo[a]pyrene-(7R,8S)-diol-(9S,10R)-epoxide.

Gu Y, Xiao B, Wargo HL, Bucher MH, Singh SV, Ji X. Gu Y, et al. Among authors: ji x. Biochemistry. 2003 Feb 4;42(4):917-21. doi: 10.1021/bi026778+. Biochemistry. 2003. PMID: 12549910

The crystal structure of mGSTA1-1 in complex with the GSH conjugate of (+)-anti-7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene (GSBpd) reveals that R216 and I221 in the last helix play important roles in catalysis [Gu, Y., Singh, S. V., and Ji, X. (2000) B …

The crystal structure of mGSTA1-1 in complex with the GSH conjugate of (+)-anti-7,8-dihydroxy-9,10-oxy-7,8,9,10-tetrahydrobenzo[a]pyrene (GS …

4

JS-K, a glutathione/glutathione S-transferase-activated nitric oxide donor of the diazeniumdiolate class with potent antineoplastic activity.

Shami PJ, Saavedra JE, Wang LY, Bonifant CL, Diwan BA, Singh SV, Gu Y, Fox SD, Buzard GS, Citro ML, Waterhouse DJ, Davies KM, Ji X, Keefer LK. Shami PJ, et al. Among authors: ji x. Mol Cancer Ther. 2003 Apr;2(4):409-17. Mol Cancer Ther. 2003. PMID: 12700285

5

Tumor cell responses to a novel glutathione S-transferase-activated nitric oxide-releasing prodrug.

Findlay VJ, Townsend DM, Saavedra JE, Buzard GS, Citro ML, Keefer LK, Ji X, Tew KD. Findlay VJ, et al. Among authors: ji x. Mol Pharmacol. 2004 May;65(5):1070-9. doi: 10.1124/mol.65.5.1070. Mol Pharmacol. 2004. PMID: 15102935 Free PMC article.

6

Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity.

Gu Y, Guo J, Pal A, Pan SS, Zimniak P, Singh SV, Ji X. Gu Y, et al. Among authors: ji x. Biochemistry. 2004 Dec 21;43(50):15673-9. doi: 10.1021/bi048757g. Biochemistry. 2004. PMID: 15595823

7

A glutathione S-transferase pi-activated prodrug causes kinase activation concurrent with S-glutathionylation of proteins.

Townsend DM, Findlay VJ, Fazilev F, Ogle M, Fraser J, Saavedra JE, Ji X, Keefer LK, Tew KD. Townsend DM, et al. Among authors: ji x. Mol Pharmacol. 2006 Feb;69(2):501-8. doi: 10.1124/mol.105.018523. Epub 2005 Nov 15. Mol Pharmacol. 2006. PMID: 16288082 Free PMC article.

8

Antitumor activity of JS-K [O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and related O2-aryl diazeniumdiolates in vitro and in vivo.

Shami PJ, Saavedra JE, Bonifant CL, Chu J, Udupi V, Malaviya S, Carr BI, Kar S, Wang M, Jia L, Ji X, Keefer LK. Shami PJ, et al. Among authors: ji x. J Med Chem. 2006 Jul 13;49(14):4356-66. doi: 10.1021/jm060022h. J Med Chem. 2006. PMID: 16821795

9

Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs.

Chakrapani H, Kalathur RC, Maciag AE, Citro ML, Ji X, Keefer LK, Saavedra JE. Chakrapani H, et al. Among authors: ji x. Bioorg Med Chem. 2008 Nov 15;16(22):9764-71. doi: 10.1016/j.bmc.2008.09.063. Epub 2008 Sep 30. Bioorg Med Chem. 2008. PMID: 18930407 Free PMC article.

10

Structure-Based Design of Anticancer Prodrug PABA/NO.

Ji X, Pal A, Kalathur R, Hu X, Gu Y, Saavedra JE, Buzard GS, Srinivasan A, Keefer LK, Singh SV. Ji X, et al. Drug Des Devel Ther. 2008;2:123-130. doi: 10.2147/dddt.s3931. Drug Des Devel Ther. 2008. PMID: 19662104 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

9,933 results

Search Page

Filters