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LXRs regulate the balance between fat storage and oxidation.
Kalaany NY, Gauthier KC, Zavacki AM, Mammen PP, Kitazume T, Peterson JA, Horton JD, Garry DJ, Bianco AC, Mangelsdorf DJ. Kalaany NY, et al. Among authors: mangelsdorf dj. Cell Metab. 2005 Apr;1(4):231-44. doi: 10.1016/j.cmet.2005.03.001. Cell Metab. 2005. PMID: 16054068 Free article.
The LXRs: a new class of oxysterol receptors.
Peet DJ, Janowski BA, Mangelsdorf DJ. Peet DJ, et al. Among authors: mangelsdorf dj. Curr Opin Genet Dev. 1998 Oct;8(5):571-5. doi: 10.1016/s0959-437x(98)80013-0. Curr Opin Genet Dev. 1998. PMID: 9794827 Review.
A natural product that lowers cholesterol as an antagonist ligand for FXR.
Urizar NL, Liverman AB, Dodds DT, Silva FV, Ordentlich P, Yan Y, Gonzalez FJ, Heyman RA, Mangelsdorf DJ, Moore DD. Urizar NL, et al. Among authors: mangelsdorf dj. Science. 2002 May 31;296(5573):1703-6. doi: 10.1126/science.1072891. Epub 2002 May 2. Science. 2002. PMID: 11988537
International Union of Pharmacology. LXII. The NR1H and NR1I receptors: constitutive androstane receptor, pregnene X receptor, farnesoid X receptor alpha, farnesoid X receptor beta, liver X receptor alpha, liver X receptor beta, and vitamin D receptor.
Moore DD, Kato S, Xie W, Mangelsdorf DJ, Schmidt DR, Xiao R, Kliewer SA. Moore DD, et al. Among authors: mangelsdorf dj. Pharmacol Rev. 2006 Dec;58(4):742-59. doi: 10.1124/pr.58.4.6. Pharmacol Rev. 2006. PMID: 17132852 Review.
221 results