Knight K - Search Results

1

The role of serial BCR-ABL transcript monitoring in predicting the emergence of BCR-ABL kinase mutations in imatinib-treated patients with chronic myeloid leukemia.

Wang L, Knight K, Lucas C, Clark RE. Wang L, et al. Among authors: knight k. Haematologica. 2006 Feb;91(2):235-9. Haematologica. 2006. PMID: 16461309

2

Clinical evaluation of BCR-ABL peptide immunisation in chronic myeloid leukaemia: results of the EPIC study.

Rojas JM, Knight K, Wang L, Clark RE. Rojas JM, et al. Among authors: knight k. Leukemia. 2007 Nov;21(11):2287-95. doi: 10.1038/sj.leu.2404858. Epub 2007 Jul 19. Leukemia. 2007. PMID: 17637811 Clinical Trial.

3

A population study of imatinib in chronic myeloid leukaemia demonstrates lower efficacy than in clinical trials.

Lucas CM, Wang L, Austin GM, Knight K, Watmough SJ, Shwe KH, Dasgupta R, Butt NM, Galvani D, Hoyle CF, Seale JR, Clark RE. Lucas CM, et al. Among authors: knight k. Leukemia. 2008 Oct;22(10):1963-6. doi: 10.1038/leu.2008.225. Epub 2008 Aug 28. Leukemia. 2008. PMID: 18754023 No abstract available.

4

Chronic myeloid leukemia patients with the e13a2 BCR-ABL fusion transcript have inferior responses to imatinib compared to patients with the e14a2 transcript.

Lucas CM, Harris RJ, Giannoudis A, Davies A, Knight K, Watmough SJ, Wang L, Clark RE. Lucas CM, et al. Among authors: knight k. Haematologica. 2009 Oct;94(10):1362-7. doi: 10.3324/haematol.2009.009134. Epub 2009 Aug 27. Haematologica. 2009. PMID: 19713230 Free PMC article.

5

Simultaneous determination of nilotinib, imatinib and its main metabolite (CGP-74588) in human plasma by ultra-violet high performance liquid chromatography.

Davies A, Hayes AK, Knight K, Watmough SJ, Pirmohamed M, Clark RE. Davies A, et al. Among authors: knight k. Leuk Res. 2010 Jun;34(6):702-7. doi: 10.1016/j.leukres.2009.11.009. Epub 2009 Dec 9. Leuk Res. 2010. PMID: 20004471

6

BCR-ABL1 tyrosine kinase activity at diagnosis, as determined via the pCrkL/CrkL ratio, is predictive of clinical outcome in chronic myeloid leukaemia.

Lucas CM, Harris RJ, Giannoudis A, Knight K, Watmough SJ, Clark RE. Lucas CM, et al. Among authors: knight k. Br J Haematol. 2010 May;149(3):458-60. doi: 10.1111/j.1365-2141.2009.08066.x. Epub 2010 Jan 11. Br J Haematol. 2010. PMID: 20067558 Free article. No abstract available.

7

BCR-ABL peptide vaccination in healthy subjects: immunological responses are equivalent to those in chronic myeloid leukaemia patients.

Rojas JM, Knight K, Watmough S, Bell J, Wang L, Callaghan T, Clark RE. Rojas JM, et al. Among authors: knight k. Leuk Res. 2011 Mar;35(3):369-72. doi: 10.1016/j.leukres.2010.05.028. Epub 2010 Jun 22. Leuk Res. 2011. PMID: 20573399

8

Naturally occurring CD4+ CD25+ FOXP3+ T-regulatory cells are increased in chronic myeloid leukemia patients not in complete cytogenetic remission and can be immunosuppressive.

Rojas JM, Wang L, Owen S, Knight K, Watmough SJ, Clark RE. Rojas JM, et al. Among authors: knight k. Exp Hematol. 2010 Dec;38(12):1209-18. doi: 10.1016/j.exphem.2010.09.004. Epub 2010 Sep 18. Exp Hematol. 2010. PMID: 20854875

9

A prospective evaluation of cardiac function in patients with chronic myeloid leukaemia treated with imatinib.

Estabragh ZR, Knight K, Watmough SJ, Lane S, Vinjamuri S, Hart G, Clark RE. Estabragh ZR, et al. Among authors: knight k. Leuk Res. 2011 Jan;35(1):49-51. doi: 10.1016/j.leukres.2010.08.020. Epub 2010 Oct 27. Leuk Res. 2011. PMID: 21030079

10

A population study showing that the advent of second generation tyrosine kinase inhibitors has improved progression-free survival in chronic myeloid leukaemia.

Francis S, Lucas C, Lane S, Wang L, Watmough S, Knight K, Bell J, Kaleel-Rahman M, Lee E, O'Brien D, Butt NM, Sadik W, De Soysa L, Seale JR, Salim R, Clark RE. Francis S, et al. Among authors: knight k. Leuk Res. 2013 Jul;37(7):752-8. doi: 10.1016/j.leukres.2013.04.003. Epub 2013 Apr 22. Leuk Res. 2013. PMID: 23618689

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