Weaver JL - Search Results

1

Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.

Matthews EJ, Kruhlak NL, Weaver JL, Benz RD, Contrera JF. Matthews EJ, et al. Among authors: weaver jl. Curr Drug Discov Technol. 2004 Dec;1(4):243-54. doi: 10.2174/1570163043334794. Curr Drug Discov Technol. 2004. PMID: 16472241

2

An evaluation of the hemizygous transgenic Tg.AC mouse for carcinogenicity testing of pharmaceuticals. I. Evidence for a confounding nonresponder phenotype.

Weaver JL, Contrera JF, Rosenzweig BA, Thompson KL, Faustino PJ, Strong JM, Ellison CD, Anderson LW, Prasanna HR, Long-Bradley PE, Lin KK, Zhang J, Sistare FD. Weaver JL, et al. Toxicol Pathol. 1998 Jul-Aug;26(4):532-40. doi: 10.1177/019262339802600409. Toxicol Pathol. 1998. PMID: 9715512

3

Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.

Kruhlak NL, Choi SS, Contrera JF, Weaver JL, Willard JM, Hastings KL, Sancilio LF. Kruhlak NL, et al. Among authors: weaver jl. Toxicol Mech Methods. 2008;18(2-3):217-27. doi: 10.1080/15376510701857262. Toxicol Mech Methods. 2008. PMID: 20020916

4

Translating New Science Into the Drug Review Process: The US FDA's Division of Applied Regulatory Science.

Rouse R, Kruhlak N, Weaver J, Burkhart K, Patel V, Strauss DG. Rouse R, et al. Ther Innov Regul Sci. 2018 Mar;52(2):244-255. doi: 10.1177/2168479017720249. Epub 2017 Jul 21. Ther Innov Regul Sci. 2018. PMID: 29568713 Free PMC article.

5

New science, drug regulation, and emergent public health issues: The work of FDA's division of applied regulatory science.

Chiu K, Racz R, Burkhart K, Florian J, Ford K, Iveth Garcia M, Geiger RM, Howard KE, Hyland PL, Ismaiel OA, Kruhlak NL, Li Z, Matta MK, Prentice KW, Shah A, Stavitskaya L, Volpe DA, Weaver JL, Wu WW, Rouse R, Strauss DG. Chiu K, et al. Among authors: weaver jl. Front Med (Lausanne). 2023 Jan 19;9:1109541. doi: 10.3389/fmed.2022.1109541. eCollection 2022. Front Med (Lausanne). 2023. PMID: 36743666 Free PMC article. Review.

6

Detection of systemic hypersensitivity to drugs using standard guinea pig assays.

Weaver JL, Staten D, Swann J, Armstrong G, Bates M, Hastings KL. Weaver JL, et al. Toxicology. 2003 Dec 1;193(3):203-17. doi: 10.1016/s0300-483x(03)00267-1. Toxicology. 2003. PMID: 14599760 Review.

7

Clinical relevance of preclinical testing for allergic side effects.

Bala S, Weaver J, Hastings KL. Bala S, et al. Toxicology. 2005 Apr 15;209(2):195-200. doi: 10.1016/j.tox.2004.12.030. Toxicology. 2005. PMID: 15767036 Review.

8

Evaluation of the Tg.AC assay: specificity testing with three noncarcinogenic pharmaceuticals that induce selected stress gene promoters in vitro and the inhibitory effects of solvent components.

Thompson KL, Rosenzweig BA, Weaver JL, Zhang J, Lin KK, Sistare FD. Thompson KL, et al. Among authors: weaver jl. Toxicol Sci. 2003 Aug;74(2):271-8. doi: 10.1093/toxsci/kfg141. Epub 2003 May 28. Toxicol Sci. 2003. PMID: 12773758

9

Evaluation of a lymph node proliferation assay for its ability to detect pharmaceuticals with potential to cause immune-mediated drug reactions.

Weaver JL, Chapdelaine JM, Descotes J, Germolec D, Holsapple M, House R, Lebrec H, Meade J, Pieters R, Hastings KL, Dean JH. Weaver JL, et al. J Immunotoxicol. 2005 Jan 1;2(1):11-20. doi: 10.1080/15476910590930100. J Immunotoxicol. 2005. PMID: 18958655 Free article.

10

The role of eNOS phosphorylation in causing drug-induced vascular injury.

Tobin GA, Zhang J, Goodwin D, Stewart S, Xu L, Knapton A, González C, Bancos S, Zhang L, Lawton MP, Enerson BE, Weaver JL. Tobin GA, et al. Among authors: weaver jl. Toxicol Pathol. 2014 Jun;42(4):709-24. doi: 10.1177/0192623314522885. Epub 2014 Apr 3. Toxicol Pathol. 2014. PMID: 24705881

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