Pala D - Search Results

1

CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts.

Shi-wen X, Stanton LA, Kennedy L, Pala D, Chen Y, Howat SL, Renzoni EA, Carter DE, Bou-Gharios G, Stratton RJ, Pearson JD, Beier F, Lyons KM, Black CM, Abraham DJ, Leask A. Shi-wen X, et al. Among authors: pala d. J Biol Chem. 2006 Apr 21;281(16):10715-26. doi: 10.1074/jbc.M511343200. Epub 2006 Feb 16. J Biol Chem. 2006. PMID: 16484225 Free article.

2

Focal adhesion kinase/Src suppresses early chondrogenesis: central role of CCN2.

Pala D, Kapoor M, Woods A, Kennedy L, Liu S, Chen S, Bursell L, Lyons KM, Carter DE, Beier F, Leask A. Pala D, et al. J Biol Chem. 2008 Apr 4;283(14):9239-47. doi: 10.1074/jbc.M705175200. Epub 2008 Feb 13. J Biol Chem. 2008. PMID: 18276598 Free PMC article.

3

Requirement of transforming growth factor beta-activated kinase 1 for transforming growth factor beta-induced alpha-smooth muscle actin expression and extracellular matrix contraction in fibroblasts.

Shi-wen X, Parapuram SK, Pala D, Chen Y, Carter DE, Eastwood M, Denton CP, Abraham DJ, Leask A. Shi-wen X, et al. Among authors: pala d. Arthritis Rheum. 2009 Jan;60(1):234-41. doi: 10.1002/art.24223. Arthritis Rheum. 2009. PMID: 19116914 Free article.

4

FAK is required for TGFbeta-induced JNK phosphorylation in fibroblasts: implications for acquisition of a matrix-remodeling phenotype.

Liu S, Xu SW, Kennedy L, Pala D, Chen Y, Eastwood M, Carter DE, Black CM, Abraham DJ, Leask A. Liu S, et al. Among authors: pala d. Mol Biol Cell. 2007 Jun;18(6):2169-78. doi: 10.1091/mbc.e06-12-1121. Epub 2007 Apr 4. Mol Biol Cell. 2007. PMID: 17409352 Free PMC article.

5

Heparan sulfate-dependent ERK activation contributes to the overexpression of fibrotic proteins and enhanced contraction by scleroderma fibroblasts.

Chen Y, Leask A, Abraham DJ, Pala D, Shiwen X, Khan K, Liu S, Carter DE, Wilcox-Adelman S, Goetinck P, Denton CP, Black CM, Pitsillides AA, Sarraf CE, Eastwood M. Chen Y, et al. Among authors: pala d. Arthritis Rheum. 2008 Feb;58(2):577-85. doi: 10.1002/art.23146. Arthritis Rheum. 2008. PMID: 18240216 Free article.

6

Rac1 signaling regulates CTGF/CCN2 gene expression via TGFbeta/Smad signaling in chondrocytes.

Woods A, Pala D, Kennedy L, McLean S, Rockel JS, Wang G, Leask A, Beier F. Woods A, et al. Among authors: pala d. Osteoarthritis Cartilage. 2009 Mar;17(3):406-13. doi: 10.1016/j.joca.2008.07.002. Epub 2008 Aug 29. Osteoarthritis Cartilage. 2009. PMID: 18760941 Free article.

7

Regulation of CCN2 mRNA expression and promoter activity in activated hepatic stellate cells.

Leask A, Chen S, Pala D, Brigstock DR. Leask A, et al. Among authors: pala d. J Cell Commun Signal. 2008 Jun;2(1-2):49-56. doi: 10.1007/s12079-008-0029-z. Epub 2008 Sep 17. J Cell Commun Signal. 2008. PMID: 18798011 Free PMC article.

8

Src kinase inhibition promotes the chondrocyte phenotype.

Bursell L, Woods A, James CG, Pala D, Leask A, Beier F. Bursell L, et al. Among authors: pala d. Arthritis Res Ther. 2007;9(5):R105. doi: 10.1186/ar2308. Arthritis Res Ther. 2007. PMID: 17927818 Free PMC article.

9

JAK3 Inhibitors: Covalent and Noncovalent Interactions of a Cyanamide Group Investigated by Multiscale Free-Energy Simulations.

Scalvini L, Pala D, Cuzzolin A, Galvani F, Lodola A, Rivara S, Mor M, Rizzi A. Scalvini L, et al. Among authors: pala d. J Chem Inf Model. 2025 Jan 16. doi: 10.1021/acs.jcim.4c01889. Online ahead of print. J Chem Inf Model. 2025. PMID: 39818786

10

Discovery of CHF-6523, an Inhaled Selective PI3Kδ Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease.

Bruno P, Pala D, Micoli A, Corsi M, Accetta A, Carzaniga L, Ronchi P, Fiorelli C, Formica M, Pizzirani D, Mazzucato R, Guariento S, Bertolini S, Martucci C, Allen AD, Mileo V, Capacchi S, Gallo PM, Fioni A, Xanxo Fernandez S, Villetti G, Puccini P, Civelli M, Guala M, Retini M, Martinelli P, Visentini F, Pavoni V, Daldosso M, Fontana S, Biagetti M, Capelli AM. Bruno P, et al. Among authors: pala d. J Med Chem. 2024 Dec 5. doi: 10.1021/acs.jmedchem.4c02062. Online ahead of print. J Med Chem. 2024. PMID: 39635891

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