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Peroxisome proliferator-activated receptor gamma recruits the positive transcription elongation factor b complex to activate transcription and promote adipogenesis.
Iankova I, Petersen RK, Annicotte JS, Chavey C, Hansen JB, Kratchmarova I, Sarruf D, Benkirane M, Kristiansen K, Fajas L. Iankova I, et al. Among authors: sarruf d. Mol Endocrinol. 2006 Jul;20(7):1494-505. doi: 10.1210/me.2005-0222. Epub 2006 Feb 16. Mol Endocrinol. 2006. PMID: 16484339 Free PMC article.
Leptin deficiency causes insulin resistance induced by uncontrolled diabetes.
German JP, Wisse BE, Thaler JP, Oh-I S, Sarruf DA, Ogimoto K, Kaiyala KJ, Fischer JD, Matsen ME, Taborsky GJ Jr, Schwartz MW, Morton GJ. German JP, et al. Among authors: sarruf da. Diabetes. 2010 Jul;59(7):1626-34. doi: 10.2337/db09-1918. Epub 2010 Apr 27. Diabetes. 2010. PMID: 20424233 Free PMC article.
Obesity is associated with hypothalamic injury in rodents and humans.
Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, Horvath TL, Baskin DG, Tschöp MH, Schwartz MW. Thaler JP, et al. Among authors: sarruf da. J Clin Invest. 2012 Jan;122(1):153-62. doi: 10.1172/JCI59660. Epub 2011 Dec 27. J Clin Invest. 2012. PMID: 22201683 Free PMC article.
14 results